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CHA_(2)DS_(2)-VASc评分对择期经皮冠脉介入术后对比剂肾病发生风险的预测价值 被引量:3

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摘要 目的探讨CHA_(2)DS_(2)-VASc评分对择期经皮冠脉介入术(PCI)后患者对比剂肾病(CIN)发生风险的预测价值。方法回顾性分析2011年8月至2018年3月于通许县人民医院住院的共712例冠心病患者的临床资料,入组患者均择期接受PCI治疗,根据是否发生CIN将入选患者分为CIN组(54例)和无CIN组(658例)。比较两组一般资料,将单因素分析有意义的变量纳入多因素logistic回归分析,评估CHA_(2)DS_(2)-VASc评分对CIN的预测效果。结果两组患者性别、左室射血分数、血肌酐、对比剂用量及CHA_(2)DS_(2)-VASc评分相比,差异有统计学意义(P<0.05)。多因素logistic回归分析结果显示,CHA 2DS 2-VASc评分[OR=3.028,95%CI:1.154~3.856,P=0.030]、血肌酐[OR=4.982,95%CI:3.252~11.362,P<0.001]、对比剂用量[OR=5.282,95%CI:1.584~13.264,P=0.003]是冠心病患者择期PCI术后发生CIN的独立危险因素。受试者工作特征(ROC)曲线显示,CHA_(2)DS_(2)-VASc评分预测CIN的灵敏度为75.6%,特异度为72.6%,AUC为0.822(95%CI:0.743~0.925),P=0.001。结论CHA_(2)DS_(2)-VASc评分可以有效预测择期PCI术后患者发生CIN的风险。
作者 刘峰
出处 《河南医学研究》 CAS 2021年第4期630-632,共3页 Henan Medical Research
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