未足月胎膜早破孕妇B族链球菌阳性率及围产结局分析

An analysis of the positive rate of group B streptococcus(GBS)screening in pregnant women with preterm premature rupture of membrane(PPROM)and the perinatal outcome

目的探究本院孕35周前未足月胎膜早破(preterm premature rupture of membrane,PPROM)孕妇中B族链球菌(group B streptococcus,GBS)筛查的阳性率及GBS阳性的PPROM孕妇的围产结局。方法选取2018年1月至2019年12月本院收治的28~35周PPROM孕妇417例,均于入院后行B族链球菌筛查,其中阳性43例为观察组,阴性374例为对照组。比较两组孕妇围产结局。结果PPROM孕妇GBS阳性率为10.3%(43/417),同期足月PROM孕妇GBS阳性率为9.2%(164/1785),差异无统计学意义。观察组宫腔感染+产褥感染发生率明显高于对照组,差异有统计学意义(P<0.05)。观察组新生儿感染及新生儿高胆红素血症发生率均明显高于对照组,差异有统计学意义(P<0.05)。观察组早产儿在儿科住院时间明显长于对照组,差异有统计学意义(P<0.05)。结论GBS携带并未增加PPROM的发生率,但PPROM孕妇中GBS阳性者围产结局更差。

Objective To understand the positive rate of group B streptococcus(GBS)screening in pregnant women with preterm premature rupture of membrane(PPROM)before 35 weeks of pregnancy in our hospital,and the positive rate of GBS-positive PPROM the perinatal outcome of pregnant women.Methods A total of 417 pregnant women with PPROM at 28 to 35 weeks who were admitted to our hospital from January 2018 to December 2019 were selected for group B streptococcus screening after admission.Among them,43 positive cases were the observation group,and 374 negative cases were the control group.The perinatal outcomes of the two groups of pregnant women were compared.Results The positive rate of GBS in the preterm group was 10.3%(43/417),and the positive rate of GBS in term PROM pregnant women during the same period was 9.2%(164/1785),the difference was not statistically significant.The incidence of uterine cavity infection+puerperal infection in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).The incidence of neonatal infection and neonatal hyperbilirubinemia in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).The pediatric hospitalization time of premature infants in the observation group was significantly longer than that in the control group,and the difference was statistically significant(P<0.05).Conclusion GBS carrying does not increase the incidence of PPROM,but the perinatal outcome of GBS-positive pregnant women with PPROM is worse.