基于肠道菌群的助脾散精法改善2型糖尿病胰岛素抵抗作用探讨

Discussion on Effect of Zhupi Sanjing Method for Improving Insulin Resistance in Type 2 Diabetes Based on Intestinal Flora

研究发现,肠道菌群失调导致的胰岛素抵抗在2型糖尿病发生发展中起关键作用。中医认为,脾失健运、精不正化是2型糖尿病的病机关键,且与肠道菌群失调关系密切。本文通过分析肠道菌群与2型糖尿病胰岛素抵抗、脾不散精与2型糖尿病胰岛素抵抗及助脾散精法调节肠道菌群、改善胰岛素抵抗的有关文献,探讨助脾散精法改善2型糖尿病胰岛素抵抗的作用机制,为临床治疗2型糖尿病提供新思路。

The study found that insulin resistance caused by intestinal flora imbalance plays a key role in the development of type 2 diabetes. According to TCM, spleen disorder and the essence from food and drink unable to be correctly transformed are the key pathogenesis of type 2 diabetes, which is closely related to intestinal flora imbalance. This article analyzed the articles about intestinal flora and type 2 diabetes insulin resistance, Pibu Sanjing(spleen unable to be concerned with distribution of the essence from food and drink) and type 2 diabetes insulin resistance, and Zhupi Sanjing(help the spleen being concerned with distribution of the essence from food and drink) method to regulate the intestinal flora and improve insulin resistance, and explored the mechanism of Zhupi Sanjing method to improve insulin resistance of type 2 diabetes, which can provide new ideas for clinical treatment of type 2 diabetes.