噻托溴铵治疗老年支气管哮喘的效果

Effect of Tiotropium Bromide on bronchial asthma in the elderly

目的探究噻托溴铵治疗老年支气管哮喘的效果。方法选择2018年5月~2020年1月辽宁省健康产业集团铁煤总医院收治的100例老年支气管哮喘患者作为研究对象。按随机数字表法分为对照组和试验组,每组各50例。对照组采用孟鲁司特与辅舒酮联合治疗,实验组则在对照组的基础上实施噻托溴铵治疗。比较两组老年支气管哮喘患者的治疗效果、症状消失时间、肺通气功能指标。结果实验组治疗总有效率高于对照组,差异有统计学意义(P<0.05);实验组呼吸困难、哮鸣音、咳嗽、胸闷等症状消失时间短于对照组,差异有统计学意义(P<0.05);两组治疗后的第一秒用力呼气容量占预计值百分比(FEV1%)、峰值呼吸流速(PEF)、用力肺活量(FVC)水平高于治疗前,差异有统计学意义(P<0.05);实验组治疗后的FEV1%、PEF、FVC水平高于对照组,差异有统计学意义(P<0.05)。结论老年支气管哮喘病患者接受噻托溴铵联合治疗,可获得较好的效果,更好地促进患者预后的改善。

Objective To explore the effect of Tiotropium Bromide on bronchial asthma in the elderly.Methods A total of 100 elderly patients with bronchial asthma who were admitted to Iron and Coal General Hospital of Liaoning Health Industry Group from May 2018 to January 2020 were selected as the research subjects.The patients were divided into control group and experimental group according to the random number table method,with 50 cases in each group.The control group was treated with Montelukast combined with Busulfan,while the experimental group was treated with Tiotropium Bromide based on the control group.Treatment effect,symptom disappearance time and pulmonary ventilation function index were compared between the two groups of elderly patients with bronchial asthma.Results The total effective rate of treatment in experimental group was higher than that in control group,the difference was statistically significant(P<0.05).The disappearance time of dyspnea,wheezing,cough,chest distress and other symptoms in the experimental group were shorter than those in the control group,the differences were statistically significant(P<0.05).The percentage of forced expiratory volume in the first second(FEV1%),peak respiratory flow rate(PEF),and forced vital capacity(FVC)levels in the two groups after treatment were higher than those before treatment,the differences were statistically significant(P<0.05).The FEV1%,PEF and FVC levels in the experimental group after treatment were higher than those in the control group,the differences were statistically significant(P<0.05).Conclusion Elderly patients with bronchial asthma receiving tiotropium bromide can get better results and better promote the improvement of patients′prognosis.