头颈部恶性肿瘤放疗相关味觉障碍的研究现状

Research status of radiotherapy-induced taste disorders in head and neck malignant tumors

味觉作为人类的五大感官之一,与我们的生活密不可分,在头颈部恶性肿瘤放疗过程中易受到损害,进而影响患者生活质量及预后。本文就放疗相关味觉障碍的流行病学特征、发病机制、影响因素、评估以及预防诊治等进行阐述,并探讨放疗相关味觉障碍的研究进展,为提高头颈部恶性肿瘤患者放疗全程中的生活质量提供新思路。

As one of the five senses of human beings,taste is inseparable from our lives.It is vulnerable to radiotherapy-induced injury for head and neck malignant tumors,which in turn affects the patients′quality of life and clinical prognosis.In this article,the epidemiological characteristics,pathogenesis,influencing factors,evaluation and prevention and treatment of radiotherapy-related taste disorders were reviewed,aiming to explore the research progress on the radiotherapy-induced taste disorders and provide novel ideas to improve the quality of life in the whole process of radiotherapy for patients with head and neck malignant tumors.