双水平气道正压无创呼吸机辅助通气治疗重症哮喘的临床观察

Clinical Observation of Bilevel Positive Airway Pressure Non-Invasive Ventilator Assisted Ventilation in the Treatment of Severe Asthma

目的:分析重症哮喘患者治疗需求,评价双水平气道正压无创呼吸机通气治疗对患者预后的影响。方法:选择本院诊治的90例重症哮喘患者,以随机数字表法分为应用氨茶碱、糖皮质激素药物等常规对症治疗的对照组(n=45)、配合双水平气道正压无创呼吸机通气治疗的观察组(n=45)。比较2组重症哮喘疾病患者治疗情况。结果:组间治疗前症状积分以及肺功能指标1s用力呼气量(FEVI)、呼气流量峰值(PEF)水平差异无显著性(P均>0.05);治疗后较治疗前改善,观察组症状积分、肺功能指标水平改善明显(P均<0.05);组间治疗总有效率比较,观察组总有效率95.55%高于对照组(P<0.05)。结论:常规对症支持治疗辅助双水平气道正压无创呼吸机通气治疗重症哮喘效果显著,可以有效地改善患者的症状、肺功能。

Objective:To analyze the treatment needs of patients with severe asthma and to evaluate the effect of bilevel positive airway pressure noninvasive ventilator ventilation on the prognosis of patients.Methods:90 patients with severe asthma in our hospital were randomly divided into control group(n=45)treated with aminophylline and glucocorticoid,and observation group(n=45)treated with bilevel positive airway pressure noninvasive ventilator.The treatment of severe asthma in the two groups was compared.Results:There was no significant difference in symptom score,forced expiratory volume(fevi)and peak expiratory flow(PEF)of pulmonary function indexes between groups before treatment(all P>0.05);after treatment,symptom scores and pulmonary function indexes of observation group improved significantly(P<0.05);the total effective rate of observation group was 95.55%higher than that of control group(P<0.05).Conclusion:Conventional symptomatic support therapy assisted with bilevel positive airway pressure noninvasive ventilator ventilation in the treatment of severe asthma has significant effect,which can effectively improve the symptoms and lung function of patients.