健脾养血祛风法调节AD的免疫屏障的研究进展

Progress on Regulating Immune Barrier of Atopic Dermatitis by Jianpi Yangxue Qufeng Decoction

特应性皮炎(atopic dermatitis,AD)又名特应性湿疹、Besnier体质性痒疹或遗传过敏性湿疹,是一种以湿疹样皮损、剧烈瘙痒及本人或其家族中可见显著的“特应性”为临床特点的皮肤病。近年来,对AD发病机制的理论不断倾向于新的免疫屏障功能的异常,目前发现健脾养血祛风法用于治疗血虚风燥型AD具有确切的疗效,可有效消除皮损,减少复发率,调节特应性皮炎的免疫屏障功能,现就关于健脾养血祛风法调节AD的免疫屏障功能的机制进行综述。

Atopic dermatitis(AD)also known as atopic eczema,Besnier prurigo diathesique or hereditary allergic eczema,is a skin disease characterized by eczema-like skin lesions,severe itching and obvious"atopy"in oneself or his family.In recent years,the theory of AD pathogenesis tends to be abnormal in immune barrier function.At present,it has been found that the method of Jianpi Yangxue Qufeng Decoction has definite curative effect in treating AD with Xuexu Fengzao type,which can effectively control skin lesions,reduce recurrence rate and regulate the immune barrier function of AD.This article reviews the mechanism of regulating the immune barrier function of AD by the method of Jianpi Yangxue Qufeng Decoction.