单通道腹腔镜治疗对妇科疾病患者炎症因子水平的影响

Effect of Single-channel Laparoscopy on the Level of Inflammatory Factors in Patients with Gynecological Diseases

目的:分析探讨单通道腹腔镜(U-LESS)治疗常见妇科良性疾病的临床疗效及其对患者血清炎症因子水平的影响。方法:选择2019年1月~2020年4月在本院妇科因良性疾病行U-LESS治疗的病例102例作为U-LESS组,同期间行多通道腹腔镜手术(CLS)的病例98例作为CLS组,分析两组患者临床资料。比较两组手术时间、术中出血量、住院天数、术后肛门排气;采用全自动生化分析仪检测两组手术前后血清IL-6、CRP、TNF-α水平;记录两组患者术后并发症发生情况。结果:两组患者手术时间、术中出血量相近(P>0.05);U-LESS组患者住院时间、术后肛门排气时间短于CLS组(P<0.05)。与手术前相比,手术后两组患者血清IL-6、CRP、TNF-α水平均显著升高,且U-LESS组IL-6、CRP、TNF-α水平低于CLS组(P<0.05)。两组术后并发症发生率相近(P>0.05)。结论:U-LESS治疗常见妇科良性疾病可减少对患者机体损伤,降低机体炎症反应。

Objective:To analyze the clinical efficacy of single-channel laparoscopy(U-LESS)in the treatment of common gynecological benign diseases and its effect on the levels of serum inflammatory factors in patients.Methods:From January 2019 to April 2020,102 patients who underwent U-LESS treatment for benign diseases in the Department of Gynecology of our hospital were selected as the U-LESS group,and 98 patients underwent multi-channel laparoscopic surgery(CLS)during the same period were selected as the U-LESS group.CLS group,analyze the clinical data of the two groups of patients.The operation time,intraoperative blood loss,hospitalization days,postoperative anal exhaust were compared between the two groups;the automatic biochemical analyzer was used to detect the levels of serum IL-6,CRP,and TNF-αbefore and after the operation of the two groups;the postoperative complications of the two groups were recorded symptoms occurred.Results:The operation time and intraoperative blood loss of the two groups were similar(P>0.05);the hospitalization time and postoperative anal exhaust time of the U-LESS group were shorter than those of the CLS group(P<0.05).Compared with before the operation,the serum levels of IL-6,CRP,and TNF-αwere significantly increased in the two groups after the operation,and the levels of IL-6,CRP,and TNF-αin the U-LESS group were lower than those in the CLS group(P<0.05).The incidence of postoperative complications in the two groups was similar(P>0.05).Conclusion:U-LESS treatment of common gynecological benign diseases can reduce the damage to the patient’s body and reduce the body’s inflammatory response.