柚皮苷二氢查尔酮的抗氧化活性研究

Studies on Antioxidant Activity of Naringin Dihydrochalcone

利用4种常见的抗氧化方法和分子对接,研究柚皮苷二氢查尔酮的抗氧化活性。通过测定酪氨酸酶活性,研究其美白活性,并用MTT试验测定其细胞毒性。试验结果表明:柚皮苷二氢查尔酮有较好的抗氧化性和美白活性,对小鼠黑色素瘤B16细胞的安全浓度为小于等于500μmol/L。

Four common antioxidant methods and molecular docking were used to study the antioxidant activity of naringin dihydrochalcone,the whitening activity of naringin dihydrochalcone was studied by measuring the activity of tyrosinase and the cytotoxicity of naringin dihydrochalcone was determined by MTT assay.The conclusion was that naringin dihydrochalcone had better antioxidant and whitening activity.The safe concentration of naringin dihydrochalcone in mice melanoma B16 cells was less than 500 mol/L.