己酮可可碱肝脏保护作用的临床研究进展

Clinical research progress of pentoxifylline on liver protection

我国肝脏疾病,尤其是非酒精性脂肪性肝病(non-alcoholic fatty liver disease)、酒精性肝病(alcoholic liver disease)和药物性肝损伤(drug-induced liver injury)的发病率及死亡率均较高。己酮可可碱(pentoxifylline)具有改善肝脏血流变、抗炎及抗纤维化等作用,对肝脏具有一定的保护作用。本文简要综述己酮可可碱肝脏保护作用的研究进展,以期为临床应用提供参考。

The incidence rate and mortality rate of liver diseases,especially nonalcoholic fatty liver disease,alcoholic liver disease and drug-induced liver injury are higher in China.Pentoxifylline can improve liver hemorheology,anti inflammation and anti fibrosis,and has a certain protective effect on liver.This article reviewed the research progress of pentoxifylline on liver protection,in order to provide reference for clinical application.