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人免疫球蛋白联合环磷酰胺治疗系统性红斑狼疮对患者疾病活动度和免疫功能的影响

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摘要 目的:探讨用人免疫球蛋白联合环磷酰胺治疗系统性红斑狼疮的效果及对患者疾病活动度和免疫功能的影响。方法:选取2017年2月至2019年7月期间在开远市人民医院接受治疗的48例系统性红斑狼疮患者,将其随机分为泼-环组(24例)与人-环组(24例)。为泼-环组患者采用泼尼松联合环磷酰胺进行治疗,为人-环组患者采用人免疫球蛋白联合环磷酰胺进行治疗。然后比较两组患者的24 h尿蛋白定量、SLEDAI评分及免疫功能指标。结果:治疗后,人-环组患者的24 h尿蛋白定量和SLEDAI评分均低于泼-环组患者,其血清IgG、IgA、IgM的水平均高于泼-环组患者,P<0.05。结论:对系统性红斑狼疮患者采用人免疫球蛋白联合环磷酰胺进行治疗的效果较好,可显著降低其疾病活动度,改善其免疫功能。
作者 庾莉菡
出处 《当代医药论丛》 2021年第3期82-83,共2页
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  • 1Helmick CG, Felson DT, Lawrence RC, et al. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States:part I. Arthritis Rheum,2008,58( 1 ) :15-25.
  • 2Cohen AS, Canoso JJ. Criteria for the classification of systemic lupus erythematosus-status 1972. Arthritis Rheum, 1972,15 (5) :540-543.
  • 3Tan EM,Cohen AS, Fries JF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum, 1982, 25 ( 11 ) :1271-1277.
  • 4Levin RE, Weinstein A, Peterson M, et al. A comparison of the sensitivity of the 1971 and 1982 American Rheumatism Association criteria for the classification of systemic lupus erythematosus. Arthritis Rheum, 1984 ;27 (5) :530-538.
  • 5Passas CM, Wong RL, Peterson M, et al. A comparison of the specificity of the 1971 and 1982 American Rheumatism Association criteria for the classification of systemic lupus erythersatosus. Arthritis Rheum, 1985,28 ( 6 ) : 620-623.
  • 6Yokohari R, Tsunematus T. Application, to the Japanese patients, of the 1982 American Rheumatism Association revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum, 1985,28(6) :693-698.
  • 7Davatchi F,Chams C, Akbarian M. Evaluation of the 1982 American Rheumatism Association revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum, 1985,28 ( 6 ) : 715.
  • 8Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1997.40 ( 9 ), 1725.
  • 9Clough JD, Elrazak M, Calabrese LH, et al. Weighted criteria for the diagnosis of systemic lupus erythematosus. Arch Intern Med, 1984, 144(2) :281-285.
  • 10Costenbader KH, Karlson EW, Mandl LA. Defining lupus cases for clinical studies:the Bosten weighted criteria for the classification of systemic lupus erythematosus. J Rheumatol, 2002, 29 ( 12 ): 2545-2550.

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