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钠-葡萄糖协同转运蛋白2抑制剂改善2型糖尿病患者心血管结局的机制探讨 被引量:13

The effect of sodium-glucose cotransporter 2 inhibitors on cardiovascular outcome in patients with type 2 diabetes mellitus and its underlying mechanism
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摘要 钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂是近年来在临床逐渐得到广泛应用的一类降糖药物。此外,目前的研究表明,除了安全有效的降糖效应以外,SGLT2抑制剂在改善心血管结局方面具有明确的益处,然而机制研究还尚不明确,目前的研究表明,SGLT2抑制剂可能从保护心脏结构和功能、延缓动脉粥样硬化进程、改善心血管高危因素等多个方面发挥保护作用。
作者 刘思默 柯静 赵冬 Liu Simo;Ke Jing;Zhao Dong(Center for Endocrine Metabolism and Immune Diseases,Beijing Luhe Hospital,Capital Medical University,Beijing Key Laboratory of Diabetes Research and Care,Beijing 101149,China)
出处 《中华糖尿病杂志》 CAS CSCD 北大核心 2021年第1期103-106,共4页 CHINESE JOURNAL OF DIABETES MELLITUS
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