1例儿童尿毒症伴腹膜炎及心功能不全的药学监护

Pharmaceutical Care for a Child with Uremia Complicated with Peritonitis and Heart Failure

腹膜炎、心功能不全为尿毒症患儿腹膜透析并发症,肾功能下降与腹膜透析均可能影响药物代谢、排泄,药物治疗应注意个体化。临床药师参与1例尿毒症并发腹膜炎、心功能不全患儿的药物治疗,与临床医生共同制定个体化治疗方案,使患儿腹膜炎相关症状好转,心功能不全改善。临床药师积极对疾病并发症、药物疗效、不良反应、相互作用等进行监护,并对患儿血药浓度的监测提出合理建议,防止不良反应的发生。

Peritonitis and heart failure are two complications of uremia. Decreased renal function and dialysis may influence the metabolism and excretion of drugs. Treatment of children with uremia should be individualized. Clinical pharmacist participated in treating one child with uremia,peritonitis and cardiac insufficiency,and made an individualized treatment plan cooperating with clinicians to improve the peritonitis related symptoms and cardiac dysfunction. Clinical pharmacist carried out pharmaceutical care in terms of disease complications,drug efficacy,adverse reactions and drug interactions,and put forward reasonable suggestions on the monitoring of blood drug concentrations of the child,so as to reduce adverse reactions.