摘要
右心室重塑是肺动脉高压的重要病理生理改变过程,而心肌纤维化是右心室重塑的主要改变之一,在右心功能不全中发挥重要作用。心脏大血管磁共振成像是评价心肌纤维化的主要手段之一,借助心肌延迟强化、T1 mapping等技术实现对心肌纤维化定性及定量评估。现就肺动脉高压心肌纤维化的磁共振评价及其在肺动脉高压临床诊断、严重度评估及预后中的价值做一综述。
Right ventricular remodeling is the key pathophysiological process in pulmonary hypertension,and myocardial fibrosis represents one of the main changes of right ventricular remodeling which plays a key role in right heart dysfunction.Cardiovascular magnetic resonance imaging(CMR)is one of the main techniques for evaluation of myocardial fibrosis,and myocardial fibrosis can be quantitatively and qualitatively evaluated using late gadolinium enhancement and T1 mapping technique.This review focused on the CMR assessment of myocardial fibrosis and its clinical value in the diagnosis,evaluation of disease severity and prognosis for pulmonary hypertension.
作者
陈小玲
陈玉成
CHEN Xiaoling;CHEN Yucheng(Department of Cardiology,West China Hospital,Sichuan University,Chengdu 610041,Sichuan,China)
出处
《心血管病学进展》
CAS
2021年第2期135-137,147,共4页
Advances in Cardiovascular Diseases
基金
四川大学华西医院学科卓越发展1·3·5工程项目资助(ZYJC18013)。
关键词
肺动脉高压
心肌纤维化
右心室
心脏大血管磁共振
Pulmonary hypertension
Myocardial fibrosis
Right ventricle
Cardiovascular magnetic resonance
