急性胰腺炎的严重度评估与重症化预测

Assessment and prediction of severity of acute pancreatitis

急性胰腺炎轻则表现为自限性,重可危及生命,临床上对病情严重程度的正确评估,将影响医师的治疗决策,目前广泛应用的严重程度分类包括改良亚特兰大分类、基于决定因素的分类等。正是由于急性胰腺炎病情的不确定性,许多预测因子,包括多因素评分系统、影像学评分和生物学标志物,已被用于预测急性胰腺炎的严重程度。文章将结合当前的研究进展,对急性胰腺炎的严重度评估与重症化预测进行具体阐述。

Acute pancreatitis(AP)can range from a mild,self-limiting disease to a severe,life-threatening disease.The accurate assessment of severity of AP will affect the decision-making of physicians.Currently,the revised Atlanta classification and the determinant-based classification are widely used clinically.Due to the uncertain course of AP,many predictors,including multifactorial scores,imaging scores and biomarkers,have been developed to predict the severity of the disease.This paper will carry on the concrete elaboration to the assessment and prediction of severity of AP based on recent advances.