基于“瘀毒”理论探究解毒活血方防治急性冠脉综合征的机理

Study on the mechanism of Jiedu Huoxue Recipe in the prevention and treatment of acute coronary syndrome based on the theory of "stasis and toxin"

急性冠脉综合征(acute coronary syndrome,ACS)的发病率逐渐升高,给家庭及社会造成沉重的负担。随着胸痛中心的大量建设,对ACS患者虽然可以积极治疗挽救心肌坏死、降低病死率,但术后总体疗效和预后与理想仍有差距。对于这种局面,我们认为预防ACS更为重要。在中医学"瘀毒"理论的基础上,对于以易损斑块破裂为病理基础的ACS,运用导师经验方解毒活血方稳定易损斑块,发挥中医药特色干预病理过程,从源头上防治心血管血栓性疾病具有积极意义。

The incidence of acute coronary syndrome(ACS)is increasing gradually, which brings great burden to the family and society.With the construction of chest pain center, although ACS patients can be actively treated to save myocardial necrosis and reduce mortali-ty, there is still a gap between the overall effect and prognosis of patients with ACS and the ideal. For this situation, we think it is more important to prevent ACS. On the basis of the theory of "stasis and toxin" in traditional Chinese medicine, for ACS based on the pathological basis of the rupture of vulnerable plaque, It is of positive significance to give full play to the characteristics of traditional Chinese medicine to intervene the pathological process and prevent and treat cardiovascular thrombotic diseases from the source.