两种不同方法直线偏振光治疗带状疱疹后神经痛的疗效观察

目的比较两种不同方法直线偏振光治疗带状疱疹后神经痛的疗效观察。方法选取52例带状疱疹后神经痛患者,随机分为常规组与按需即时组,每组各26例。常规组给予直线偏振光治疗1次/d,按需即时组每日照射次数不设限制,当疼痛视觉模拟评分(VAS)24分并有镇痛需求时,及时给予直线偏振光治疗,同一照射部位两次治疗间隔时间N4h;两组设定10d为1个疗程。观察记录治疗前,治疗1d后、10d后(翌日清晨)VAS评分,治疗后1h、4h、24 h和10d疗程结束后不良反应的指标,统计分析两组患者疼痛VAS评分、睡眠改善情况及临时加用镇痛药物的次数,对治疗效果与安全性进行评定。结果治疗前两组患者VAS评分及睡眠时间差异无统计学意义(P>0.05),治疗后按需即时组VAS评分低于常规组、睡眠时长较常规组长,临时加用镇痛药物次数少于常规组,差异具有统计学意义(P<0.05),两组不良反应差异无统计学意义(P>0.05)。结论比较两种不同方法直线偏振光治疗带状疱疹后神经痛,个体化的按需即时组的镇痛效果优于常规组,可改善患者睡眠状况,减少加用镇痛药物次数,安全有效。

Objective To compare the therapeutic effects of two different methods of linearly polarized light on postherpetic neuralgia.Methods 52 patients with postherpetic neuralgia were selected and randomly divided into routine group and on—demand immediate group with 26 cases each.The routine group was treated with linearly polarized light once a day.Patients in the on—demand immediate group did not limit daily irradiation times.When the pain visual analogue scale(VAS)score was points and there was a need for analgesia,Enearly polarized light was given immediately,and the interval time at the same irradiation site was hours.Two groups set 10 days as a course of treatment.VAS scores before treatment,1 day after treatment,10 days after treatment(early in the morning the next day),adverse reaction indexes at 1,4,24 hours after treatment and 10 days after treatment were observed and recorded.The pain VAS scores,sleep improvement and the times of temporary addition of analgesic drugs in the two groups of patients were statistically analyzed to evaluate the treatment effect and safety.Results There was no significant difierence in VAS score and sleep time between the two groups before treatment(P>0.05).After treatment,the VAS score of the on—demand immediate group was lower than that of the conventional group,the sleep time was longer than that of the conventional group leader,and the number of times of temporary addition of analgesic drugs was lower than that of the conventional group,with significant difierence(P<0.05).There was no diHerence in adverse reactions between the two groups(P>0.05).Conclusion Comparing the two different methods of linearly polarized light for the treatment of postherpetic neuralgia,the individualized on—demand immediate group has better analgesic effect than the conventional group,which can improve the sleep status of patients,reduce the number of times of adding analgesic drugs,and is safe and efiective.