渐进性肌肉放松训练联合肠内营养对胃癌化疗患者负性情绪与免疫功能的影响

Effects of progressive muscle relaxation training combined with enteral nutrition on negative emotion and immune function in patients with gastric cancer undergoing chemotherapy

目的探讨分析渐进性肌肉放松训练联合肠内营养对胃癌化疗患者负性情绪与免疫功能的影响。方法选取本院2017年3月~2019年2月期间收治的83例胃癌化疗患者作为主要研究对象。采用随机数字表法进行分组,对照组41例患者给予肠内营养进行干预,观察组42例患者在对照组基础上增加渐进性肌肉放松训练联合干预。观察对比两组患者干预前后焦虑抑郁情绪、睡眠质量、营养状况、免疫功能及生活质量变化。结果干预后,观察组患者的SDS、SAS和PSQI评分明显低于对照组,SF-36评分明显高于对照组(P<0.05);观察组血清白蛋白、总蛋白及CD3+、CD4+、CD4+/CD8+水平明显高于对照组,CD8+水平明显低于对照组(P<0.05)。结论渐进性肌肉放松训练联合肠内营养能够有效缓解胃癌化疗患者的焦虑抑郁情绪,提升机体营养状况及免疫功能,改善其睡眠和生活质量,值得临床推广应用。

Objective To analyze the effects of progressive muscle relaxation training combined with enteral nutrition on negative emotion and immune function in patients with gastric cancer undergoing chemotherapy. Methods A total of 83 patients with gastric cancer undergoing chemotherapy in our hospital from March 2017 to February 2019 were collected and randomly divided into two groups :the control group(41 cases)were given enteral nutrition intervention. On this basis, the observation group(42 cases)were given progressive muscle relaxation training. The changes of anxiety and depression,sleep quality,nutritional status,immune function and life quality before and after intervention between the two groups were observed and compared. Results After intervention,self-rating depression scale(SDS),elf-rating anxiety scale(SAS)and pittsburgh sleep quality index scale(PSQI)scores in the observation group were lower than those in the control group,and the 36-item shot-form health status survey scores were higher than those in the control group(P<0.05). Serum albumin,total protein and CD3+,CD4+,CD4+/CD8+ levels in the observation group were higher than those in the control group,while CD8+ levels were significantly lower than those in the control group(P<0.05). Conclusion Progressive muscle relaxation training combined with enteral nutrition can effectively relieve the anxiety and depression of patients with gastric cancer undergoing chemotherapy,improve the nutritional status and immune function,and improve sleep and life quality,which is worthy of clinical application.