右美托咪定对小儿腹腔镜手术麻醉恢复期躁动的影响

Effects of dexmedetomidine on restlessness during the convalescent period of anesthesia in laparoscopic surgery in children

目的:探讨对采取腹腔镜手术治疗的小儿患者应用右美托咪定对患儿术后麻醉恢复期躁动的影响。方法:选取100例采取腹腔镜治疗的患儿并随机分成试验组与对照组,每组各50例,在麻醉诱导前30 min予以患儿静脉注射0.5μg/kg右美托咪定,对照组予以患儿注射等剂量的0.9%NaCl溶液,两组后续麻醉方案及治疗均一致,评价两组患儿麻醉效果、恢复期躁动及不良反应发生情况。结果:在麻醉、苏醒及解除麻醉至恢复室等时间指标上两组差异无统计学意义(P>0.05);试验组恢复期躁动总发生率为6.00%,明显低于对照组20.00%的总发生率,差异有统计学意义(P<0.05);试验组患儿术后不良反应总发生率为2.00%,对照组为16.00%,组间对比差异有统计学意义(P<0.05)。结论:对腹腔镜手术治疗的患儿,麻醉诱导前使用右美托咪定可有效降低术后麻醉恢复期躁动的发生率,值得推广。

Objective To investigate the effect of dexmedetomidine on postoperative restlessness in pediatric patients undergoing laparoscopic surgery.Method 100 cases of laparoscopic treatment of children were selected and randomly divided into experimental group and control group.50 cases in each group,and 30 min before anesthesia induction to children with intravenous 0.5μg/kg right beautiful mi set,the control group gives children the isodose physiological saline injections,two groups of subsequent anesthesia methods and treatment are consistent,the efficacy of the two groups of children with anesthesia,recovery agitation and adverse reactions occur were evaluated.Results There was no significant difference between the two groups in terms of time indexes such as anesthesia,resuscitation and recovery room(P>0.05).The total incidence of restlessness in the recovery period of the experimental group was 6.00%,significantly lower than the total incidence of 20.00%in the control group(P<0.05).The total incidence of postoperative adverse reactions was 2.00%in the experimental group and 16.00%in the control group,and the difference between the groups was statistically significant(P<0.05).Conclusion Before induction of anesthesia,dexmedetomidine can effectively reduce the incidence of agitation during recovery from anesthesia in children undergoing laparoscopic surgery,which is worthy of promotion.