超声测定不同孕期子宫动脉搏动指数、阻力指数和S/D值可预测妊娠期高血压孕妇病情

Correlation between UtA-PI,UtA-RI and S/D values measured by ultrasound in different pregnancy periods and the prediction of the condition of pregnant women with hypertension in pregnancy and the maternal and infant outcome Screening Fetal Down's Syndrome

目的分析不同孕期孕产妇患者超声测定的子宫动脉搏动指数(UtA-PI)、阻力指数(UtA-RI)和S/D值与妊娠期高血压疾病(HDCP)孕妇病情预测及母婴结局的相关性。方法选择我院2018年1月~2019年12月间收治的162例符合纳入标准的HDCP患者作为观察组,正常妊娠孕妇100例作为对照组。妊娠早期(10~14周)、妊娠中期(20~23周)、妊娠晚期(30~31周)行超声检查并记录UtA-PI、UtA-RI和S/D;用logistics回归模型分析UtA-PI、UtA-RI和S/D值与HDCP孕妇母婴结局关系,绘制ROC曲线分析UtA-PI、UtA-RI和S/D值预测HDCP的价值。结果妊娠中期和妊娠晚期,观察组UtA-PI、UtA-RI和S/D值均高于对照组(P<0.05);妊娠中期和妊娠晚期,超声检查UtA-PI、UtA-RI和S/D值鉴别诊断HDCP的敏感度和特异度均高于85%,且AUC均大于0.9;妊娠中期和妊娠按期妊娠异常组HDCP孕妇UtA-PI、UtA-RI和S/D值均高于正常妊娠组(P<0.05);妊娠中期和妊娠晚期,HDCP孕妇超声检查的UtA-PI、UtA-RI和S/D值均是影响妊娠结局的独立性威胁因素(P<0.05)。结论超声测定孕妇UtA-PI、UtA-RI和S/D值可有效预测HDCP,且UtA-PI、UtA-RI和S/D值是影响妊娠结局的独立性威胁因素。

Objective To analyze the correlation between the UtA-PI,UtA-RI and S/D values measured by ultrasound in pregnant women of different pregnancy periods and the hypertensive disorder complicating pregnant(HDCP)women's disease prediction and maternal and infant outcomes.Methods A total of 162 HDCP patients who reach the inclusion criteria from January 2018 to December 2019 in our hospital were selected as the observation group,and 100 normal pregnant women were used as the control group.Ultrasound examination was performed in the first trimester(10-14 weeks),the second trimester(20-23 weeks),and the third trimester(30-31 weeks)to record UtA-PI,UtA-RI and S/D.The relationship between UTA PI,UTA RI and S/D was analyzed by logistic regression model.The ROC curve was used to analyze the value of UTA PI,UTA RI and S/D in predicting HDCP.Results The UtA-PI,UtA-RI and S/D values of the observation group during the second and third trimester were significantly higher than those of the control group,and the difference was significant(P<0.05).The sensitivity and specificity of UtA-RI and S/D values for differential diagnosis of HDCP are higher than 85%,and the AUC was greater than 0.9.The values of UtA-PI,UtA-RI and S/D of HDCP pregnant women in the second and third trimester pregnancy abnormal pregnancy groups were higher than those of normal pregnancy group(P<0.05).UtA-PI,UtA-RI and S/D values of ultrasonography of HDCP pregnant women during the second and third trimesters were independent of the outcome of pregnancy Threats(P<0.05).Conclusion The value of UTA-PI,UTA-RI and S/D measured by ultrasound can effectively predict HDCP.The value of UTA-PI,UTA-RI and S/D are independent threat factors affecting pregnancy outcome.