期刊文献+

老年人癫痫的药物治疗 被引量:2

Drug therapy for epilepsy in the elderly
原文传递
导出
摘要 癫痫在老年人中较为常见,但老年癫痫患者因共患疾病较多、合并用药种类较多及药代动力学的特殊性等,导致老年人癫痫的药物治疗较为困难。本文对老年人癫痫药物治疗的选择、不良反应、代谢情况及药物相互作用进行综述。 Epilepsy is a common disease in the elderly,but drug therapy for epilepsy faces difficulties due to comorbidities,drug combinations and altered pharmacokinetics in the elderly.This article reviews the selection,adverse reactions,metabolism and drug interactions of epilepsy drugs in the elderly.
作者 刘慧菁 刘银红 Liu Huijing;Liu Yinhong(Department of Neurology,Division of Health and Medical Service,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China)
出处 《中华老年医学杂志》 CAS CSCD 北大核心 2021年第2期260-264,共5页 Chinese Journal of Geriatrics
关键词 癫痫 药物疗法 Epilepsy Drug therapy
  • 相关文献

参考文献2

二级参考文献22

  • 1Karceski S, Morrell MJ, Carpenter D. Treatment of epilepsy in adults : expert opinion, 2005. Epilepsy Behav, 2005, 7 Suppl 1 : S1-64.
  • 2French JA, Kanner AM, Bautista J, et al. Efficacy and tolerability of the new antiepileptic drugs I. Treatment of new onset epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology, 2004, 62: 1252-1260.
  • 3Perucca E, Gram L, Avanzini G, et al. Antiepileptic drugs as a cause of worsening seizures. Epilepsia, 1998, 39 : 5-17.
  • 4Kwan P, Brodie MJ. Early identification of refractory epilepsy. N Engl J Med, 2000, 342: 314-319.
  • 5Marson AG, Al-Kharusi AM, Alwaidh M, et al. The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. Lancet, 2007, 369 : 1016-1026.
  • 6Beghi E, Gatti G, Tonini C, et al. Adjunctive therapy versus ahernative monotherapy in patients with partial epilepsy failing on a single drug: a muhicentre, randomized, pragmatic controlled trial. Epilepsy Res, 2003, 57: 1-13.
  • 7Kwan P, Brodie MJ. Epilepsy after the first drug fails : substitution or add-on? Seizure, 2000, 9: 464468.
  • 8Hauser WA. Seizure disorders: the changes with age. Epilepsia, 1992, 33 Suppl 4: $6-14.
  • 9Wallace H, Shorvon S, Tallis R. Age-specific incidence and prevalence rates of treated epilepsy in an unselected population of 2,052,922 and age-specific fertility rates of women with epilepsy. Lancet, 1998, 352: 1970-1973.
  • 10Faught E. Monotherapy in adults and elderly persons. Neurology, 2007, 69 (24 Suppl 3 ) : $3-$9.

共引文献186

同被引文献27

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部