右美托咪定复合布托啡诺用于剖宫产术后患者自控静脉镇痛的效果及对患者术后疲劳和宫缩痛的影响

Effect of Dexmedetomidine Combined with Butorphanol on Patient-controlled Intravenous Analgesia after Cesarean Section and Its Influence on Postoperative Fatigue and Contractile Pain

目的:探索剖宫产术后予以布托啡诺联合右美托咪定自控静脉镇痛后对患者疼痛情况、术后疲劳和宫缩痛的影响。方法:选取2018年5月~2019年4月于某院行剖宫产的初产妇120例,将其按照随机数字表法分为对照组和研究组,对照组产妇术后仅予以布托啡诺处理,研究组产妇术后则予以布托啡诺+右美托咪定处理,采用视觉疼痛评分(VAS)、疲劳评分量表(FSS)、镇静评分量表(OAA/S)对患者术后的镇痛效果及疲劳状态进行评估。结果:布托啡诺+右美托咪定后产妇镇静深度明显增加(P<0.05);两种药物联合使用后产妇宫缩痛得到明显缓解(P<0.05);两种药物联合使用后产妇术后3d疲劳状态得到有效缓解(P<0.05)。结论:剖宫产术后自控静脉镇痛将布托啡诺+右美托咪定联合使用能有效缓解宫缩疼痛,增加镇静深度,缓解患者疲劳状态。

Objective:To explore the effect of dexmedetomidine combined with butorphanol on patient-controlled intravenous analgesia after cesarean section and its influence on postoperative fatigue and contractile pain.Methods:120 primiparas who underwent cesarean section in a hospital from May 2018 to April 2019 were divided into two groups according to the method of random number table.The control group was only treated with butorphanol after operation,while the study group was treated with butorphanol combined with dexmedetomidine after operation.The visual pain score(VAS),fatigue rating scale(FSS),and sedation rating scale(OAA/S)were used to evaluate postoperative analgesic effect and fatigue status.Results:The depth of sedation was significantly increased after butorphanol and dexmedetomidine treatment(P<0.05).The pain of uterine contraction was significantly relieved after the combination of the two drugs(P<0.05).The fatigue state of three days after the combination of the two drugs was effectively relieved(P<0.05).Conclusion:The combination of butorphanol and dexmedetomidine can effectively relieve the pain of uterine contraction,increase the depth of sedation and relieve the fatigue of patients.