多西他赛治疗晚期乳腺癌的临床研究

Clinical Study of Docetaxel for Advanced Breast Cancer

目的:探讨多西他赛治疗晚期乳腺癌的临床疗效。方法:选取2017年5月~2019年11月在某院接受治疗的晚期乳腺癌患者112例,分为研究组和对照组各56例,对照组采取常规治疗模式,研究组在此基础上结合多西他赛进行治疗,观察比较两组患者疗效和不良反应发生率。结果:治疗后,研究组有效率为92.6%,显著高于对照组有效率79.6%(P<0.05);治疗后,研究组不良反应发生率明显低于对照组(P<0.05)。结论:对晚期乳腺癌患者应用多西他赛进行治疗,可显著提高患者的身心健康,减轻社会及其个人的直接和间接经济负担,提高患者的成本效益比,可进一步在临床治疗上进行推广。

Objective:To study the clinical effect of docetaxel on advanced breast cancer.Methods:112 cases of advanced breast cancer patients who were treated in a hospital from May 2017 to November 2019 were selected and divided into study group and control group,with 56 cases in each group.The control group was treated with routine treatment,and the study group was treated with docetaxel based on the control group,then the efficacy and incidence of adverse reactions were observed and compared between the two groups.Results:After treatment,the effective rate of the study group was 92.6%,which was significantly higher than that of the control group(79.6%,P<0.05).After treatment,the incidence of adverse reactions in the study group was significantly lower than that in the control group(P<0.05).Conclusion:The application of docetaxel in the treatment of advanced breast cancer can significantly improve the physical and mental health of patients,reduce the direct and indirect economic burden of society and individuals,and improve the cost-benefit ratio of patients,which can be further promoted in the clinical treatment.