成人供者双肾移植的临床应用及进展

Clinical application and progress on adult donor dual kidney transplantation

充分利用边缘供者器官是扩大供者池、缓解器官短缺的重要手段。经过恰当的供者评估、分配和受者选择,成人供者双肾移植(DKT)既可以获得与单肾移植(SKT)类似的临床效果,又能有效降低边缘供肾的弃用率。本文对成人供者DKT的临床应用和进展做一综述,从DKT的发展概况、分配标准、受者选择、手术方式及外科并发症、临床效果等方面进行阐述,旨在为今后开展边缘供者DKT工作提供借鉴与指导。

Full application of marginal donor organs is a critical method to expand donor pool and alleviate organ shortage.After accurate donor evaluation,allocation and recipient selection,adult donor dual kidney transplantation(DKT)can not only achieve equivalent clinical efficacy to single kidney transplantation(SKT),but also effectively reduce the discard rate of marginal donor kidney.In this article,the clinical application and progress on adult donor DKT were reviewed from the perspectives of the development situation,allocation standard,recipient selection,surgical methods and complications as well as clinical efficacy of DKT,aiming to provide reference and guidance for subsequent development of marginal donor DKT.