郴州市39例新型冠状病毒肺炎确诊病例病毒核酸检测结果分析

Detection results of viral nucleic acid in 39 confirmed COVID-19 cases in Chenzhou City

目的分析郴州市39例新型冠状病毒肺炎(简称新冠肺炎)确诊病例不同时期不同标本的新型冠状病毒核酸检测情况,为新冠肺炎临床诊疗和管理提供科学依据。方法以郴州市新冠肺炎疫情期间确诊的39例新冠肺炎病例为研究对象,收集其从确诊、住院诊疗到院后康复管理过程中新型冠状病毒核酸检测的相关信息,描述不同阶段、不同标本的检测结果。结果新冠肺炎疫情期间,郴州市共完成了39例新冠肺炎确诊病例301人次核酸检测。新冠肺炎病例均以单独咽拭子标本核酸检测确诊,出院后随访复查采用同一病人不同种类标本联合检测为主。出院后病例新冠病毒核酸检测复阳率为12.82%。结论增加病例不同时期标本核酸检测次数和同一时期不同种类标本联合检测可提高阳性检出率,应对出院后病例"复阳"现象开展进一步研究并加强健康管理。

Objective To analyze the detection of viral nucleic acid at different stages of the disease and in different types of specimens in 39 confirmed COVID-19 cases in Chenzhou City,and to provide a scientific basis for clinical diagnosis,treatment and management of COVID-19.Methods Thirty-nine confirmed COVID-19 cases during the epidemic period of COVID-19 in Chenzhou City served as the research subjects.The relevant information of viral nucleic acid detection in the process of diagnosis,hospitalization and post-hospital rehabilitation management was collected to describe the detection results at different stages of the disease and in different types of specimens.Results During the COVID-19 epidemic,a total of 301 nucleic acid tests were completed for 39 confirmed cases of COVID-19 in Chenzhou City.COVID-19 cases were confirmed by nucleic acid test of throat swab specimens alone,and the combined specimen test was mainly used for follow-up after discharge.The positive rate of retesting viral nucleic acid after discharge was 12.82%.Conclusions Increasing the number of nucleic acid test and combined test of different specimens at the same stage can improve the positive detection rate of specimens.It is necessary to conduct further research on re-positive cases of nucleic acid test in discharged patients with COVID-19,and strengthen health management.