摘要
1例76岁男性因右侧肢体无力伴言语不清3 h入院,诊断为急性脑梗死。入院48 min后给予静脉溶栓治疗。溶栓后患者症状明显好转,提示溶栓有效。溶栓后20 min,患者出现病情变化,考虑为阿替普酶(rt-PA)所致的过敏反应,经积极对症处理后,患者病情稳定,但加重了神经功能缺损体征,后期经脑梗死二级预防治疗及康复训练,患者好转出院。
A 76-year-old man was admitted in the hospital due to right limb weakness and unclear speech for 3 h.The man was diagnosed with acute cerebral infarction.Intravenous thrombolysis was given at 48 min after admission.After thrombolysis,the patient’s symptoms improved significantly,suggesting that thrombolysis is effective.At 20 min after thrombolysis,the patient’s condition changed.It was considered to be anaphylactic reaction caused by alteplase(rt-PA).After active symptomatic treatment,the patient’s condition was stable,but the signs of neurological deficit were aggravated.After secondary preventive treatment and rehabilitation training for cerebral infarction,the patient improved and discharged.
作者
曾军燕
赵雄飞
ZENG Junyan;ZHAO Xiongfei(Neurology Department,Meishan Cardio Cerebrovascular Disease Hospital,Meishan 620000,China)
出处
《临床医学研究与实践》
2021年第7期24-25,28,共3页
Clinical Research and Practice
关键词
阿替普酶
急性脑梗死
过敏反应
急性哮喘发作
alteplase
acute cerebral infarction
anaphylactic reaction
acute asthma attack
