干细胞在唇腭裂患者牙槽突裂中应用的研究进展

Research progress of stem cells in the treatment of alveolar cleft in patients with cleft lip and palate

干细胞具有自我更新能力及多向分化潜能,已被广泛应用于多个领域。相对于唇腭裂患者牙槽突裂的常规手术治疗方法,干细胞具有来源广泛、取材方便、免疫原性低等优点,整形外科医生已逐渐关注唇腭裂患者牙槽突裂干细胞治疗的研究。该文对胚胎干细胞、人间充质干细胞、颌面部来源干细胞在唇腭裂患者牙槽突裂中应用的研究进展进行了综述。

Stem cells have self-renewal ability and multi-directional differentiation potential,and they have been widely used in many fields.Compared with the conventional surgical treatment of cleft lip and palate,stem cells have many advantages including wide sources,convenient materials,and low immunogenicity.At present,plastic surgeons have gradually paid attention to the research of stem cell treatment of cleft lip and palate patients.This article describes the research progress of embryonic stem cells,human mesenchymal stem cells,and maxillofacial stem cells in the treatment of alveolar clefts in patients with cleft lip and palate.