超声评价睡眠不足与颈动脉粥样硬化的相关性分析

Analysis of the Correlation between Lack of Sleep and Carotid Atherosclerosis

目的:观察分析超声评价睡眠不足与颈动脉粥样硬化的相关性。方法:选取2019年2月至2019年12月平原县中医院收治的颈动脉粥样硬化患者86例作为研究对象,按照睡眠时间分为对照组和观察组,每组43例。睡眠时间<7 h的患者为观察组,并选取同时段睡眠时间>7 h患者作为对照组,均采用超声检查。采用统计学分析2组研究对象的颈动脉内膜-中层厚度与颈总动脉血流动力学参数、颈总动脉弹性功能参数以及相关性。结果:观察组颈动脉内膜-中层厚度、血管阻力指数明显高于对照组,差异有统计学意义(P<0.05),收缩期峰值血流速度、舒张末期血流速度低于对照组,差异有统计学意义(P<0.05);收缩期内径、舒张期内径、脉压以及僵硬度指数明显高于对照组,差异有统计学意义(P<0.05);Person相关性分析颈动脉内膜-中层厚度与血管阻力指数、僵硬度指数密切相关,差异有统计学意义(P<0.05)。结论:睡眠不足与颈动脉粥样硬化之间存在密切相关性,通过超声检测可进行有效评价。

Objective:Observe and analyze the correlation between sleep deprivation and carotid atherosclerosis in ultrasound evaluation.Methods:A total of 86 patients with carotid atherosclerosis in Pingyuan County Hospital of traditional Chinese medicine from February 2019 to December 2019 were selected as the research objects and divided into control group and observation group according to sleep time,43 cases in each group.Patients with sleep time less than 7 h were selected as the observation group,and patients with sleep time more than 7 h were selected as the control group.The correlation between carotid intima-media thickness and common carotid artery hemodynamic parameters,common carotid artery elastic function parameters were analyzed statistically.Results:The carotid intima-media thickness and vascular resistance index were significantly higher than those of the control group(P<0.05),and the peak blood flow velocity during systole and end-diastolic blood flow velocity were lower than those of the control group(P<0.05).The systolic diameter,diastolic diameter,pulse pressure and stiffness index were significantly higher than those of the control group(P<0.05).Person correlation analysis carotid artery intima-media thickness was closely related to vascular resistance index and stiffness index(P<0.05).Conclusion:There is a close correlation between lack of sleep and carotid atherosclerosis,which can be effectively evaluated by ultrasound detection.