反射式共聚焦显微镜在感染性皮肤病中的应用

Applicaton of reflectance confocal microscopy in infectious skin diseases

反射式共聚焦显微镜(RCM),是皮肤科新兴的诊断手段,在很多疾病的应用方面日趋成熟。RCM目前已经广泛应用于皮肤肿瘤和色素皮肤疾病的诊疗。本研究总结了多种常见感染性皮肤病RCM表现:疱疹性皮肤病,见表皮水疱内高折光圆盘细胞;扁平疣为颗粒层及棘层上部细胞呈同心圆样排列;玫瑰痤疮毛囊内见蠕形螨过度繁殖;手足癣RCM真菌菌丝检出率较高;手足口病见表皮内密集多房性小水疱等。希望RCM能为常见感染性皮肤病的诊断及鉴别诊断提供更多帮助。

Reflectance confocal microscopy(RCM),it is a new diagnostic method in dermotology,and the application for diagnosis of many skin diseases is becoming more and more mature.RCM has been widely used in the diagnosis and treatment of skin tumors and pigmentation skin deseases.This paper summarizes the RCM manifestations of several common infectious dermatoses:Herpetic dermatosis,high refractive disc cells can be seen in the epidermis;Verruca plana,the cells of stratum granulosum and upper stratum spinosum arrange in concentric circles;Rosacea,demodex overbreeding in hair follicles;In tinea manus and pedis,the detection rate of fungi is high by RCM;Hand-food-mouth disease,dense multilocular blisters in epidermis.It is hoped that RCM will provide more help for the diagnosis and differential diagnosis of common infectious dermatoses.