摘要
烧伤是皮肤软组织损伤较常见的病因,给患者带来极大的生理及心理负担。目前临床上对大面积烧伤的救治仍有较大的局限性。近年来,关于干细胞治疗皮肤烧伤创面的组织工程研究备受关注。本文归纳、总结间充质干细胞治疗烧伤创面的临床前研究和临床试验性研究,并对MSC应用于烧伤创面修复的研究进展作一综述。
Burn is a common cause of skin and soft tissue injury,which brings great physiological and psychological burden to patients.Currently,there are still great limitations in the treatment of large area burn in clinical practice.In recent years,tissue engineering research on stem cell therapy for skin burn wounds has attracted much attention.In this paper,preclinical and experimental studies on the treatment of burn wounds by mesenchymal stem cell(MSC)were summarized,and the research progress on the application of MSC in burn wound repair was reviewed.
作者
王宏宇
刘玲英
巴特
Wang Hongyu;Liu Lingying;Ba Te(Inner Mongolia Medical University, Huhhot 010059, China;Department of Burns, Institute of Burns Medicine, Inner Mongolia BaoGang Hospital, Baotou 014010, China;Department of Burns and Plastic Surgery, Fourth Medical Center of PLA General Hospital, Beijing 100048, China)
出处
《中华损伤与修复杂志（电子版）》
CAS
2020年第6期495-498,共4页
Chinese Journal of Injury Repair and Wound Healing(Electronic Edition)
基金
国家自然科学基金青年项目(81701900)
解放军总医院科技创新苗圃基金项目(17KMM28)
解放军总医院扶持基金项目(2017FC-304M-CXYY-01)
解放军总医院转化医学项目(2017TM-029)
内蒙古自治区自然科学基金项目(2015MS0815,2020MS08022)
内蒙古医科大学科技百万工程(联合)项目[YKD2016KJBW(LH)041]。
关键词
烧伤
伤口愈合
间质干细胞
组织工程
Burns
Wound healing
Mesenchymal stem cells
Tissue engineering
