人参蛋白质组学研究进展

Research progress on proteomics of ginseng

人参具有很高的药用价值和广泛的药理活性,蛋白质对于人参次级代谢产物的产生和营养价值的体现具有重要意义。运用蛋白质组学的思路和技术可绘制人参的蛋白质表达谱,以评价人参的药用活性与差异蛋白质之间的相关性,同时还可研究人参活性成分的生物合成途径等。通过总结国内外的相关文献,从样品制备、差异蛋白质组分析及功能蛋白质研究等方面对人参蛋白质组学的相关研究进展进行综述,为人参蛋白质组学的系统化研究提供参考。

Ginseng shows high medicinal value and extensive pharmacological activities, and the proteins are of great importance for the production of secondary metabolites and the realization of nutritive value of ginseng. Proteomics ideas and techniques can be used to draw the protein expression profile of ginseng, evaluate the correlation between the medicinal activities and differential proteins of ginseng, as well as research the biosynthesis pathway of active constituents of ginseng. By summarizing the relevant domestic and foreign literatures, this paper reviews the relevant research advances of ginseng proteomics from the following aspects: sample preparation, differential proteome analysis, functional protein research and so on, in order to provide reference for the systematic study of ginseng proteomics.