摘要
肿瘤复发与转移是晚期肿瘤患者死亡的主要原因之一。循环肿瘤细胞是推动肿瘤进展到转移的基础,而上皮间质转化(EMT)是肿瘤进展到转移的关键过程。该文综述了EMT在肿瘤侵袭转移过程中分子机制。
Tumor recurrence and metastasis are one of the main death causes in patients with advanced cancer.Circulating tumor cells(CTCs)are prerequisite for tumor progression to metastasis,while epithelial-mesenchymal transition(EMT)is pivotal for tumor progression to metastasis.The molecular mechanism ofEMT on tumor invasion and metastasis has been reviewed.
作者
李奇栋
许庆文
孙利君
LI Qi-dong;XU Qing-wen;SUN Li-jun(Department of Gastrointestinal Surgery,Affiliated Hospital of Guangdong Medical University,Zhanjiang 524000,China)
出处
《广东医科大学学报》
2021年第1期10-13,39,共5页
Journal of Guangdong Medical University
关键词
循环肿瘤细胞
上皮间质化
转移
circulating tumor cells
epithelial-mesenchymal transition
metastasis