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循环肿瘤细胞上皮间质转化的研究进展 被引量:2

Epithelial-mesenchymal transition of circulating tumor cells
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摘要 肿瘤复发与转移是晚期肿瘤患者死亡的主要原因之一。循环肿瘤细胞是推动肿瘤进展到转移的基础,而上皮间质转化(EMT)是肿瘤进展到转移的关键过程。该文综述了EMT在肿瘤侵袭转移过程中分子机制。 Tumor recurrence and metastasis are one of the main death causes in patients with advanced cancer.Circulating tumor cells(CTCs)are prerequisite for tumor progression to metastasis,while epithelial-mesenchymal transition(EMT)is pivotal for tumor progression to metastasis.The molecular mechanism ofEMT on tumor invasion and metastasis has been reviewed.
作者 李奇栋 许庆文 孙利君 LI Qi-dong;XU Qing-wen;SUN Li-jun(Department of Gastrointestinal Surgery,Affiliated Hospital of Guangdong Medical University,Zhanjiang 524000,China)
出处 《广东医科大学学报》 2021年第1期10-13,39,共5页 Journal of Guangdong Medical University
关键词 循环肿瘤细胞 上皮间质化 转移 circulating tumor cells epithelial-mesenchymal transition metastasis
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