血小板衍生物在组织再生研究和应用中的标准化管理

Standardized management of platelet derivatives for tissue regeneration research and applications

目的总结血小板衍生物在组织再生研究与应用中的标准化管理方式。方法查阅近年来国内外血小板衍生物在组织再生研究与应用中出现的瓶颈问题和标准化管理措施的相关文献,并进行分析和总结。结果尽管血小板衍生物越来越多地用于骨关节、皮肤、神经、肌腱韧带、颌面外科等多种组织再生重建研究,但因制备方法差异大、命名不规范、报告系统不完善以及缺乏制备过程的量化和标准化管理等问题,造成了研究与应用结果的不确定性和不可比性。近年来国际发展呈现出标准化研究与质量管理趋势。结论实行标准化研究与质量管理将有助于促进血小板衍生物在再生修复领域的研究与应用。

Objective To summary the standardized management in research and applications of platelet derivatives for tissue regeneration.Methods The related literature about bottlenecks and standardized management of platelet derivatives in recent years was reviewed and analyzed.Results Although the platelet derivatives are increasingly used to accelerate the regenerative processes of injured joint,skin,nerve,ligament/tendon,and alveolar bone,etc.,the large variation in preparation methods,diverse nomenclature,incomplete reporting system,and lack of quantitative and standardized management of the preparation process have caused uncertainty and incomparability of research and application results.In recent years,there has been a trend towards standardized research and management of platelet derivatives.Conclusion The implementation of standardized research and quality management will contribute to promote the research and application of platelet derivatives in the field of tissue regeneration.