摘要
子痫前期是指妊娠妇女在孕20周后出现以血压升高及蛋白尿为主要症状的产科常见疾病,是导致全世界孕产妇发病率和病死率增加的主要原因之一。越来越多的证据表明,子痫前期对母体的影响不仅局限于妊娠及产褥期,有子痫前期史的妇女远期罹患心血管疾病、肾脏疾病、代谢综合征、血栓栓塞以及糖尿病等疾病的风险增加。加强风险因素评估、早期干预和临床监测将有益于降低子痫前期女性远期不良预后发生风险,对防治子痫前期相关的心血管疾病、肾脏疾病等具有重要意义。
Preeclampsia refers to a common obstetric disease with elevated blood pressure and proteinuria as the main symptoms after 20 weeks of gestation,which is one of the main reasons leading to the rise in maternal morbidity and mortality worldwide.There is growing evidence that the maternal effects of preeclampsia are not limited to pregnancy and puerperium.Women with preeclampsia are at increased risk of developing cardiovascular disease,kidney disease,metabolic syndrome,thromboembolism and diabetes in the future.Strengthening assessment of risk factors,early intervention and clinical monitoring will help reduce the risk of long-term adverse prognosis for women with preeclampsia,which is of great significance for the prevention and treatment of preeclampsiarelated cardiovascular diseases,kidney diseases and so on.
作者
许煌坊
李笑天
XU Huang-fang;LI Xiao-tian(Obstetrics and Gynecology,Shanghai key hiboratory of Female Reproductive Endocrine-Related Diseases,Institute of Biomedical Sciences,Hospital of Fudan University,Shanghai 200011,China)
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2021年第2期142-145,共4页
Chinese Journal of Practical Gynecology and Obstetrics
基金
上海市临床科技创新重点项目(18511105602)
上海市女性生殖疾病重点临床医学中心(2017ZZ01016)
国家“十三五”规划重大项目(2016YFC1000400)
国家重点基础研究发展规划(973计划)(2015CB943300)。
关键词
子痫前期
心血管疾病
应激试验
预后
防治
preeclampsia
cardiovascular diseases
stress test
prognosis
prevention and treatment
