正畸联合双颌手术治疗前牙区严重骨性开[牙合]长期稳定性的Meta分析

Meta-analysis of the long-term stability of serious anterior skeletal open-bite malocclusion after orthodontic surgery

目的评价正畸正颌联合治疗前牙区严重骨性开[牙合]的长期稳定性。方法全面检索SCI、Medline、Pubmed、Cochrane Library、EMBASE、Springer、DOI等外文数据库以及中国期刊全文数据库、中国生物医学文献数据库、中文科技期刊数据库、维普数据库、万方数据库等中文数据库中相关的随机对照试验(RCT)、半随机对照试验以及临床病例对照试验(CCT)文献。由2名学者进行文献的筛选、数据提取及质量评价,将满足质量标准的文献进行Meta分析。结果最终纳入6篇符合要求的文献,均为自身前后对照实验,共220例患者。Meta分析结果显示,术后与至少术后1年SNA、SNB、ANB、MP-PP、SN-PP、N-Me、ANS-Me、S-G0、OB、OJ、L1-MP/(°)、L1-MP/mm、U1-PP/(°)、U1-PP/mm均无统计学差异,但MP-SN有统计学差异。结论正颌外科联合正畸治疗前牙区严重骨性开[牙合]除下颌有一定的复发外总体上保持了长期的稳定性。

Objective The aim of this systematic review was to analyse the long-term stability of a serious anterior skeletal open-bite malocclusion with orthodontic combined surgical treatments.Methods Data were obtained from SCI,Medline,PubMed,Cochrane Library,EMBASE,Springer,DOI and other foreign databases,such as Chinese Biomedical Literature Database,China National Knowledge Infrastructure database,VIP database for Chinese technical periodicals,the digital journal of Wan Fang Data and other Chinese databases.The literatures,which consisted of randomised controlled trials,quasi-randomised controlled trials and clinical case-control trials,were selected and evaluated independently by two investigators in accordance with the inclusion and exclusion criteria.Then,Meta-analysis was performed on the literatures that met the inclusion criteria.Results The six references(five foreign articles and one Chinese article)that met the requirements were pre-post case-control studies with a total of 220 patients.Meta-analysis showed that SNA,SNB,ANB,MP-PP,SN-PP,N-Me,ANS-Me,S-G0,OB,OJ,L1-MP/(°),L1-MP/mm,U1-PP/(°)and U1-PP/mm before operation and at least 1 year after operation had no statistical difference,whereas MP-SN had statistical difference.Conclusion Orthodontic and surgical treatment for serious anterior skeletal open-bite malocclusion could keep relative stability,except a little replace of the mandibular.