硝苯地平与硫酸镁对妊高征孕妇血压水平的控制效果

Effect of nifedipine and magnesium sulfate on blood pressure of pregnant women with pregnancy induced hypertension

目的研究在妊高征孕妇中使用硝苯地平和硫酸镁进行治疗对血压水平的控制效果。方法将2018年7月至2019年12月本院收治的120例妊高征病人作为研究对象,根据治疗方案的不同将病人分为研究组和参照组,两组各60例。参照组病人接受硫酸镁治疗,研究组病人接受硝苯地平结合硫酸镁治疗,对比两组病人治疗前后血压变化及不良事件发生率。结果治疗后,研究组病人血压指数明显低于参照组,差异较大(P<0.05);研究组不良事件发生率(5.00%)比参照组不良事件发生率(16.67%)低,差异较大(P<0.05)。结论对妊高征孕妇使用硝苯地平结合硫酸镁治疗能有效降低血压水平,且不良事件较少。

Objective:To study the effect of nifedipine and magnesium sulfate on blood pressure control in pregnancy induced hypertension(PIH).Methods:120 cases of PIH patients in our hospital from July 2018 to December 2019 were selected as the research objects.According to the different treatment schemes,the patients were divided into study group and reference group,with 60 cases in each group.Patients in the reference group received magnesium sulfate treatment,while patients in the study group received nifedipine combined with magnesium sulfate treatment.Blood pressure changes and incidence of adverse events were compared between the two groups before and after treatment.Results:After treatment,the blood pressure index of the study group was significantly lower than that of the reference group(P<0.05).The incidence of adverse events in the study group(5.00%)was lower than that in the reference group(16.67%),and the difference was significant(P<0.05).Conclusion:Nifedipine combined with magnesium sulfate can effectively reduce the blood pressure level of pregnant women with pregnancy induced hypertension syndrome,and has less adverse events,which is worthy of promotion.