探讨子宫颈癌的临床病理特征和影响盆腔淋巴结转移的Logistic危险因素分析

To explore the clinicopathological characteristics of cervical cancer and Logistic risk factors affecting pelvic lymph node metastasis

目的探究与分析子宫颈癌的临床病理特征和影响盆腔淋巴结转移的Logistic危险因素分析结果。方法回顾性分析本院自2017年12月至2019年12月收治的65例子宫颈癌患者的临床以及术后病理资料,按照是否发生淋巴结转移分为淋巴结转移组(n=19例)及淋巴结未转移组(n=46例),采用单因素以及多因素的Logistic回归分析该组子宫颈癌临床病理特征以及影响盆腔淋巴结的转移危险因素。结果行Logistic分析可见,影响子宫颈癌合并发生盆腔淋巴结转移的危险因素包括了肿瘤直径≥2cm、肿瘤浸润深度>1/2子宫颈全层、存在宫旁浸润、肿瘤累及子宫下段(P<0.05)。结论影响子宫颈癌合并发生盆腔淋巴结转移的危险因素包括了肿瘤直径≥2cm、肿瘤浸润深度>1/2子宫颈全层、存在宫旁浸润、肿瘤累及子宫下段等,妇科工作者需要根据盆腔淋巴结转移情况实施规范性的盆腔淋巴结切除术等其他措施,以达到促进预后的目的。

Objective:To explore and analyze the clinicopathological characteristics of cervical cancer and the results of Logistic risk factor analysis affecting pelvic lymph node metastasis.Methods:The clinical and postoperative pathological data of 65 patients with cervical cancer treated in our hospital from December 2017 to December 2019 were retrospectively analyzed.They were divided into lymph node metastasis group(n=19 cases)and lymph nodes non-metastatic group(n=46 cases)according to whether lymph node metastasis occurred.In the non-metastatic group(n=46 cases),univariate and multivariate Logistic regression were used to analyze the clinicopathological characteristics of cervical cancer in this group and the risk factors affecting the metastasis of pelvic lymph nodes.Results:Logistic analysis showed that the risk factors affecting cervical cancer combined with pelvic lymph node metastasis include tumor diameter≥2 cm,tumor invasion depth>1/2 of full cervical layer,presence of parauterine invasion,and tumor involvement in the lower uterine segment(P<0.05).Conclusion:The risk factors that affect cervical cancer and pelvic lymph node metastasis include tumor diameter≥2cm,tumor invasion depth>1/2 of full cervical layer,presence of parauterine invasion,and tumor involvement in lower uterine segment.Gynecologists need to be based on pelvic lymph node metastasis,other measures such as standardized pelvic lymphadenectomy are implemented to promote the prognosis.