女童不完全性性早熟多因素分析及预防保健措施研究

Analysis of multifactors of incomplete precociousness of girls and study of preventive health care measures

目的分析女童不完全性性早熟的诱发因素,为高危女童提供早期切实可行的预防措施,以降低发病率,促进其身心健康成长。方法采用病例对照研究,选取2017年10月~2019年12月于潍坊医学院附属医院儿科门诊就诊并诊断为不完全性性早熟的98例女童为病例组,对照组为同一时间于儿童保健门诊接受健康查体的196例女童。采用t检验分析病例组和对照组儿童年龄等指标的差异,采用χ~2检验分析两组儿童出生情况、生活方式等的差异。以是否为不完全性性早熟为因变量建立Logistic回归模型,分析不同生活习惯等对女童不完全性性早熟发病的影响。结果病例组和对照组儿童在经常看手机等电子设备,误服避孕药,经常食用反季蔬果,喜食肉类、油炸食品,母亲初潮年龄早,家庭中使用较多塑料制品,母亲孕期使用保胎药,家庭关系是否和睦,低出生体重,经常看情感类电视节目,使用成人洗漱用品,自觉学习负担大等指标存在差异,且差异有显著性(P<0.05),Logistic回归分析显示,经常看手机等电子设备,误服避孕药,喜食肉类、油炸食品,母亲初潮年龄早,家庭中使用较多塑料制品,母亲孕期使用保胎药,家庭关系不和睦,经常看情感类电视节目,使用成人洗漱用品,自觉学习负担大均为女童不完全性性早熟的危险性因素(OR<1,P<0.05)。结论引起女童不完全性性早熟的诱发因素依次为经常看手机等电子设备,误服避孕药,喜食肉类、油炸食品,母亲初潮年龄早,家庭中使用较多塑料制品,母亲孕期使用保胎药,经常看情感类电视节目,使用成人洗漱用品,自觉学习负担大等因素,家庭关系和睦为不完全性性早熟的保护因素。指导儿童合理、科学的饮食,培养良好健康的生活习惯,营造家庭和谐安全的成长环境,对减少女童性早熟有一定的指导意义。

Objective To analyze the pre-ego factors of incomplete sexual precociousness in girls,to provide early and practical preventive measures for girls at high risk,to reduce morbidity and to promote their physical and mental health.Methods Using the guidelines of the Ministry of Health for sexual precocious diagnosis and treatment,a case-control study was used to select 98 girls who were treated and diagnosed as incomplete precocious in the pediatric clinic of the Affiliated Hospital of Weifang Medical University from October 2017 to December 2019,and 196 girls who received health check-ups at the same time at the children’s health clinic.The differences in the age of children in the case group and the control group were analyzed by t-test,and the differences in birth and lifestyle of the two groups were analyzed byχ~2-test.Logistic regression model was established for the factor variable whether or not incomplete sexual precociousness was established,and the effects of different living habits on the incidence of incomplete sexual precociousness in girls were analyzed.Results Children in the case group and children in the control group often looked at electronic devices such as mobile phones,mistakenly taking birth control pills,often eating anti-season fruits and vegetables,eating meat,eating fried food,early mother tide age,family use of more plastic products,mother pregnancy use of birth protection pills,family relationship harmony,low birth weight,often watch emotional TV programs,use adult toiletries,consciously learn to bear the burden of large indicators there were differences,and the difference was statistically significant(P<0.05),Logistic regression analysis showed that often look at mobile phones and other electronic devices,mistakenly take birth control pills,like meat,happy to eat fried food,mother early tide,more plastic products used in the family.The use of fetal medicine during pregnancy,family relations are not harmonious,often watch emotional television programs,the use of adult toiletries,conscious learning burden was mostly girls incomplete sexual precocious risk factors(OR<1,P<0.05).Conclusion The inducing factors that cause girls to be incomplete sexual precocious are,in turn,regularly watching electronic devices such as mobile phones,mistaking birth control pills,eating meat,fried food,early mother’s early tide,using more plastic products in the family,mother’s use of fetal medicine during pregnancy,often watching emotional TV programs,using adult toiletries,consciously learning to bear a large burden and other factors,family relations and harmony as the protective factor of incomplete sexual precociousness.There is guiding significance to guide children to eat reasonably and scientifically,cultivate good and healthy living habits and create a harmonious and safe environment for families to grow up.