可吸收聚左旋乳酸骨固定系统在小儿心脏手术中的应用

Poly L-lactic acid absorbable bone fixation system for pediatric cardiac operation

目的总结可吸收聚左旋乳酸骨固定系统在小儿心脏手术中的应用效果和经验。方法2014年1月至2017年12月,广州市妇女儿童医疗中心共完成4424例小儿心脏外科手术,根据入选和排除标准筛选,1967例入选,按照是否使用可吸收聚左旋乳酸骨固定系统分为使用组(A组)和未使用组(B组)。A组1015例,男650例,女365例;年龄1个月~4.7岁,中位年龄6.3个月;体质量3.6~20.0 kg,中位值6.4 kg。B组952例,男570例,女382例;年龄1个月~4.2岁,中位年龄6.1个月;体质量3.4~20.0 kg,中位值6.5 kg。结果术后因胸骨活动致伤口愈合不良并行清创缝合术者A组3例(0.29%),B组18例(1.89%),两组差异有统计学意义(P=0.001)。结论可吸收聚左旋乳酸骨固定系统可以有效减少小儿心脏手术后因胸骨活动致伤口愈合不良的发生率。

Objective To summarize effect of poly L-lactic acid absorbable bone fixation system for preventing poor wound healing after pediatric cardiac operation.Methods From January 2014 to December 2017,4424 patients underwent cardiac operations at our center.There were 1967 patients included.According to the usage of poly L-lactic acid absorbable bone fixation system,they were classified into group A(1015 cases)and group B(952 cases).The age and body weight at surgery was 1 month to 4.7 years and 3.6-20.0 kg in group A,and the age and body weight at surgery was 1 month to 4.2 years and 3.4-20.0 kg in group B.Results After operation,the incidence of debridement and suturing operation for poor wound healing was 0.29% in group A,and 1.89% in group B.Two groups of incidence had significant difference(P=0.001).Conclusion Poly L-lactic acid absorbable bone fixation system decreased the incidence of poor wound healing after pediatric cardiac operation.