三种自动勾画软件应用于中上腹部危及器官勾画的准确性研究

Study on the Accuracy of Three Automatic Delineation Softwares for the Delineation of Organs at Risk in Abdomen

目的比较三种自动勾画软件(Pinnacle 9.10、LinkingMed和Manteia)勾画上腹部危及器官(OAR)的准确性。方法选取了26例上腹部肿瘤患者,由一名资深的临床医师手动勾画OAR(肝脏、脊髓、双肾、胰腺和胃),并采用三种软件对其进行自动勾画。以手动勾画为金标准,计算并比较三种自动勾画结果的质心偏差(Center of Mass Deviation,DC)、Dice相似性系数(Dice Similarity Coefficient,DSC)、Hausdorff距离(Hausdorff Distance,HD)、包容性指数(Inclusive Index,IncI)和敏感性指数(Sensitivity Index,SI)。采用单因素方差分析评价各项指标的统计学差异,同时比较了三种软件勾画结果的准确性。结果肝、双肾和脊髓的DC、DSC、HD、IncI和SI,LinkingMed和Manteia组与Pinnacle组有统计学差异(P<0.05),inkingMed和Manteia组的勾画效果优于Pinnacle组。对于胃和胰腺的结果,Manteia组优于Lingkingmed组,除了IncI,均有统计学差异。结论对于肝、肾和脊髓,这三种软件均有较好的勾画效果,LinkingMed和Manteia的勾画效果更优于Pinnacle软件。对于胃和胰腺,Manteia的勾画效果优于LinkingMed。

Objective To compare the accuracy of three kinds of automatic delineation software(Pinnacle 9.10,Linkingmed and Manteia)in delineating upper abdominal organs at risks(OARs).Methods The OARs(liver,spinal cord,kidneys,pancreas and stomach)was manually drawn by a senior clinician in 26 patients with upper abdominal tumors,and three kinds of software were used to automatically draw the OARs.By the standard of the manual delineation,the index of center of mass deviation(DC),dice similarity coefficient(DSC),Hausdorff distance(HD),inclusive index(IncI)and sensitivity index(SI)were compared for three kinds of segmentation results.One-way analysis of variance was used to evaluate the statistical difference of each index,and the accuracy of the three software was compared.Results There were significant differences in DC,DSC,HD,IncI and SI of the liver,kidneys and spinal cord between the Lingkingmed and Manteia,groups with the pinnacle group(P<0.05).The automatic delineation results in Lingkingmed and Manteia were both better than those in Pinnacle.For the results of stomach and pancreas,Manteia group was better than Lingkingmed group,there were signficantly differences(P<0.05)in Lingkingmed and Manteia,except for IncI.Conclusion All three softwares of auto-segmentation can satisfactorily contour the liver,kidneys and spinal cord.The performance in Lingkingmed and Manteia was better than Pinnacle,and Manteia was better than Lingkingmed in the delineation of stomach and pancreas.