肾嗜酸细胞腺瘤影像表现及病理特征分析

The Study of Imaging Features and Pathological Features of Renal Oncocytoma

目的分析肾嗜酸细胞腺瘤(RO)的影像资料及病理特征,提高对该病的诊断。方法回顾性分析经病理证实的29例RO患者的影像学及病理学资料。结果肿瘤主要位于肾皮质,多呈类圆形,可出现囊变及假包膜。平扫密度或信号多变,强化峰值多位于皮质或实质期。中央瘢痕及节段性增强反转是其特征性表现。免疫组织化学以CD117、EMA、Ki-67阳性率较高。CT增强参数中,A2、C2与CD117呈正性相关关系(P<0.05);A3、B3、C3与CD10呈正性相关关系(P<0.05);C2与CK7呈正性相关关系(P=0.009)。结论CT增强参数可能在一定程度上反映RO免疫组化指标表达情况。当出现上述影像征象时,RO是可供考虑的鉴别诊断之一。

Objective To analyze the imaging data and pathological features of renal eosinophilic adenoma(RC)and to improve the diagnosis of the disease.Methods The imaging and pathological data of29 patients with RO confirmed by pathology were retrospectively analyzed.Results The tumor was mainly located in the renal cortex,and it was mostly round,and there were cystic changes and pseudo-envelops.The sweep density or signal is variable,and the enhanced peak is mostly located in the cortex or the parenchyma.Central scar and segmental enhancement reversal are characteristic features.Immunohistochemistry had a higher positive rate of CD117,EMA,and Ki-67.Among the a enhancement pa ra meters,A2,C2 and CD117 were positively correlated(P<0.05);A3,B3,C3 and CD10 were positively correlated(P<0.05);C2 was positively correlated with CK7(P=0.009).Conclusion CT enhancement parameters may reflect the expression of RO immunohistochemistry indicators to some extent.When the above image signs appear,RO is one of the differential diagnoses to consider.