β-TCP植入与口腔修复膜覆盖治疗对颌骨囊肿术后骨缺损的修复效果分析

Effect ofβ-TCP Combined with Oral Repair Membrane on Bone Defect Restoration after Jaw Cyst Excision

目的:分析β-磷酸三钙人工骨(β-TCP)植入与口腔修复膜覆盖治疗对颌骨囊肿术后骨缺损的修复效果。方法:选取2018年7月~2019年9月我院颌骨囊肿患者116例,采用随机数字表法将其分为对照组和观察组,每组各58例。对照组经囊肿摘除术刮治后对创面采用口腔修复膜覆盖治疗,观察组经囊肿摘除术刮治后放置β-TCP充填骨缺损并采用口腔修复膜覆盖治疗。比较两组患者的临床疗效、骨缺损区电子计算机断层扫描(computed tomography,CT)值以及丧失功能牙术后恢复情况。结果:术后,观察组总有效率明显高于对照组(P<0.05);术后3个月时,两组患牙缺损区CT值均明显高于术前(P<0.05);术后6个月时,两组患牙缺损区CT值均明显高于术后3个月及术前(P<0.05),患牙恢复情况均明显优于术后3个月(P<0.05),术后12个月时,两组患牙缺损区CT值均明显高于术前、术后3个月及术后6个月(P<0.05),患牙恢复情况均明显优于术后3个月及6个月(P<0.05),且术后3个月、6个月及12个月时,观察组骨缺损区CT值明显高于对照组(P<0.05),患牙恢复情况明显优于对照组(P<0.05)。结论:在手术刮治后采用β-TCP填充联合口腔修复膜覆盖治疗颌骨囊肿患者可有效促进成骨及患牙恢复,具有较好疗效。

Objective:To analyze the effect ofβ-tricalcium phosphate artificial bone(β-TCP)implantation and oral repair membrane covering on bone defect restoration after jaw cyst excision.Methods:116 patients with jaw cyst in our hospital from July 2018 to September 2019 were selected and randomly divided into control group and observation group,with 58 cases in each group.The control group underwent curettage after cyst excision,however,the observation group was filled withβ-TCP and covered with membrane after the curettage.The clinical efficacy,computed tomography(CT)value of bone defect area,and postoperative recovery of the lost function teeth were compared between two groups.Results:After the operation,the total effective rate of observation group was obviously higher than that of control group(P<0.05);at 3 months after operation,the CT values of the defect area in both groups were obviously higher than those before the operation(P<0.05);at 6 months after operation,the CT values of the defect area were obviously higher than those at 3 months after operation and before operation(P<0.05),and the recovery of the affected teeth in both groups was obviously better than that at 3 months after operation(P<0.05);at 12 months after the operation,the CT values of the defect area and the recovery of affected teeth in both groups were obviously higher and better than those at 3 and 6 months after operation and before operation(P<0.05);at 3,6,and 12 months after operation,the CT values of bone defect area and the recovery of affected teeth in the observation group were obviously higher and better than those in the control group(P<0.05).Conclusion:The use ofβ-TCP combined with oral repair membrane can effectively promote osteogenesis and tooth recovery in patients with jaw cyst.