临床药师干预住院医嘱对抗菌药物合理应用的影响

To Explore the Effect of Clinical Pharmacists's Intervention on the Rational Use of Antimicrobial Agents

目的:探讨临床药师干预住院医嘱对抗菌药物合理应用的影响。方法:选取2018年5月至2019年5月偃师市人民医院实施临床药师干预前住院患者113例作为对照组;选取2019年6月至2020年6月偃师市人民医院实施住院医师+临床药师干预后住院患者113例作为观察组。统计并比较两组抗菌药物使用不合理情况,比较两组住院时间、住院费用和抗菌药物使用费用。结果:观察组抗菌药物使用不合理发生率为2.65%,低于对照组的11.50%,差异有统计学意义(P<0.05)。观察组住院时间(12.82±2.12)d,短于对照组的(16.93±2.14)d;住院费用(5710.43±200.03)元、抗菌素使用费用(918.67±30.50)元,均低于对照组的(5813.62±200.19)元、(1000.89±30.59)元,差异有统计学意义(P<0.05)。结论:临床药师干预住院医嘱能够促进抗菌药物合理应用,降低抗菌药物使用不合理发生率,从而减轻患者治疗费用负担,缩短住院时间。

Objective:To investigate the effect of clinical pharmacists's intervention on the rational use of antimicrobial agents.Methods:113 patients hospitalized before clinical pharmacist intervention in Yanshi People's Hospital from May 2018 to May 2019 were selected as the control group;113 patients hospitalized after clinical pharmacist intervention in Yanshi People's Hospital from June 2019 to June 2020 were selected as the observation group.The unreasonable use of antibacterial drugs was calculated and compared between the two groups.The hospitalization time,hospitalization cost and antimicrobial drug use cost were compared between the two groups.Results:The incidence of unreasonable antimicrobial use in observation group was 2.65%,lower than that in the control group(11.50%),with statistical difference(P<0.05).Length of hospital stay in observation group(12.82±2.12)d;shorter than that in the control group(16.93±2.14)d,the cost of hospitalization(5710.43±200.03)yuan,and the cost of antibiotics(918.67±30.50)yuan,all lower than the control group(5813.62±200.19)yuan,(1000.89±30.59)yuan,with statistical difference(P<0.05).Conclusion:The intervention of clinical pharmacist in inpatient orders can promote the rational use of antimicrobial agents,reduce the incidence of irrational use of antimicrobial agents,thus reducing the burden of treatment costs and shortening the length of hospital stay.