核素TID比值诊断非梗阻性冠心病心肌缺血

The Clinical Value of TID Ratio of Radionuclide Gated Exercise/Resting Myocardial Perfusion Imaging in the Diagnosis of Myocardial Ischemia in Non-Obstructive Coronary Heart Disease

目的利用核素门控运动/静息心肌灌注显像半定量指标左心腔一过性缺血性扩张(TID)比值来诊断非梗阻性冠心病患者心内膜下心肌缺血。方法非梗阻性冠心病32例(冠状动脉造影或冠脉CTA狭窄小于50%),有心绞痛症状;健康对照组30例,无高血压、无肥胖、无糖尿病。分别行运动/静息状态下核素门控心肌灌注显像。采用Siemens Ecam双探头SPECT仪器心脏软件对数据进行处理分析,计算出TID比值。结果非梗阻性冠心病组:运动/静息TID比值为1.31±0.27,总灌注缺损率(TPD)65.6%;健康对照组:运动/静息TID比值为0.94±0.20,总灌注缺损率(TPD)3.3%。结论核素TID比值是诊断非梗阻性冠心病心内膜下心肌缺血的有效且无创的较佳指标。

Objective To apply semi-quantitative Index of radionuclide gated exercise/resting Myocardial Perfusion Imaging(TID)ratio of transient Ischemic dilatation of left ventricular cavity in the diagnosis of subendocardial Myocardial Ischemia in patients with non-obstructive Coronary Heart Disease.Methods 32 cases of non-obstructive coronary heart disease(coronary angiography or coronary CTA stenosis less than 50%),with symptoms of angina pectoris were collected for the observation group,while 30 cases of healthy control were selected,with no hypertension,no obesity and no diabetes.Radionuclide gated myocardial perfusion imaging was performed in exercise/resting state,respectively.The heart software of Siemens ecam dual-probe SPECT instrument was used to process and analyze the data,and the TID ratio was calculated.Results For the non-obstructive coronary heart disease group,exercise/resting TID ratio was 1.31±0.27,and total perfusion defect(TPD)rate was 65.6%,while for the healthy control group,exercise/rest TID ratio was 0.94±0.20,and total perfusion defect rate(TPD)was 3.3%.Conclusion Radionuclide TID ratio is an effective and non-invasive index for the diagnosis of subendocardial myocardial ischemia in non-obstructive coronary heart disease.