期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

孕早期甲状腺素水平对妊娠期糖尿病发病的影响

下载PDF
导出
摘要 选择2019年1月至12月50例甲状腺功能正常孕妇作为A组,50例单纯TPOAb阳性的孕妇作为B组,50例单纯低甲状腺素血症孕妇作为C组,检测三组孕妇孕早期的甲状腺功能,分析不同孕妇的甲状腺素水平的妊娠糖尿病发病率。结果 C组1h、2h血糖TSH水平高于A组、B组(P<0.05),FT4水平低于A组、B组,但三组的FT3水平比较(P>0.05),A组GDM发病率为4%,B组为16%,C组为36%(P<0.05)。结论孕早期单纯甲状腺过氧化物酶抗体阳性、单纯低甲状腺素血症可影响糖代谢指标,增加妊娠糖尿病发生风险。
作者 陈艳红
机构地区 洛阳牡丹妇产医院产科
出处 《实用糖尿病杂志》 2021年第1期104-105,共2页 Journal of Practical Diabetology
关键词 孕早期 妊娠期糖尿病(GDM) 发病率 甲状腺素(TH)
分类号 R714.256 [医药卫生—妇产科学]
  • 相关文献

参考文献5

二级参考文献65

  • 1Shan ZY,Chen YY,Teng WP,et at. A study for maternal thyroid hor- mone deficiency during the first half of pregnancy in China[ J]. Eur J Clin Invest,2009,39( 1 ) :37-42.
  • 2Pop VJ,Kuijpens JL,van Baar AL,et al. Low maternal free thyroxine concentrations during early pregnancy are associated with impaired psychomotor development in infancy [ J ]. Clin Endocrinol (Oxf) , 1999,50(2) :149-155.
  • 3Pop V J, Bronwers EP, Vader HL, et al. Maternal hopythyroxinaemia during early pregnancy and subsequent child development : a 3-year follow-up study [ J]. Clin Endocrinol (Oxf) ,2003,59 (3) :282-288.
  • 4Li Y,Shan Z,Teng W,et al. Abnormalities of maternal thyroid func- tion during pregnancy affect neuropsychological development of their children at 25-30 months[ J]. Clin Endocrinol (Oxf) ,2010,72 ( 6 ) : 825 -829.
  • 5Henrichs J, Bongers-Schokking JJ, Sehenk JJ, et al. Materal thyroid function during early pregnancy and cognitive functioning in early childhood:The generation R study [ J ]. J Clin Endocrinol Metab, 2010,95 ( 9 ) :4227-4234.
  • 6Cleary-Goldman J, Malone FD, Lambert-Messerlian G, et al. Mater- nal thyroid hypofuction and pregnancy outcomes [ J ]. Obsterics and Gynecology,2008,112 ( 1 ) :85-92.
  • 7Casey BM, Dashe JS, Spong CY, et al. Perinatal significance of isola- ted maternal hypothyroxinemia identified in the first half of pregnancy [ J ]. Obstet Gynecol, 2007,109 ( 5 ) : 1129-1135.
  • 8Hamm MP, Cherry NM, Martin JW, et al. The impact of isolated ma- ternal hypothyroxinemia on perinatal morbidity [ J ]. J Obstet Gynae- col Can,2009,31 ( 11 ) :1015-1021.
  • 9Potlukova E, Potluka O, Jiskra J, et al. Is Age a Risk Factor for Hypo- thyroidism in Pregnancy? An Analysis of 5223 Pregnant Women[ J ]. J Clin Endocrinol Metab,2012,97(6) :1945-1952.
  • 10Pearce EN, Oken E, Gillman MW,et al. Association of first-trimester thyroid function test values with thyroperoxidase antibody status, smoking, and multivitamin use [ J ]. Endocr Pract, 2008,14 ( 1 ) : 33 - 39.

共引文献60

实用糖尿病杂志
2021年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部