星蒌承气汤治疗中风之痰热腑实证患者的临床疗效

Clinical Effect of Xingkirilou Chengqi Decoction in Treating Stroke with Phlegm and Heat

目的探讨星蒌承气汤治疗中风之痰热腑实证患者的临床疗效。方法将2018年2月至2019年3月我院收治的110例中风之痰热腑实证患者随机分为两组,各55例。研究组采用星蒌承气汤治疗,对照组仅采用常规治疗。比较两组患者治疗后主要中医证候、血流动力学指标、血小板参数及临床疗效。结果研究组治疗后半身不遂为(4.37±0.63)分、偏身麻木为(1.14±0.41)分、言语謇涩为(1.25±0.57)分、口舌歪斜为(0.95±0.13)分、咳痰为(0.68±0.18)分、头痛为(0.81±0.22)分、腹满为(0.94±0.26)分、便干便秘为(1.25±0.52)分、总分为(11.42±1.27)分,明显低于对照组的(5.66±0.75)分、(1.97±0.35)分、(2.03±0.41)分、(1.42±0.26)分、(1.44±0.39)分、(1.83±0.62)分、(1.90±0.33)分、(2.17±0.57)分、(15.04±2.04)分,差异均有统计学意义(P<0.05)。研究组治疗后血浆黏度为(1.42±0.37)mpa·s、血液高切黏度为(10.27±2.63)mpa·s、血液低切黏度为(4.38±0.94)mpa·s、平均血小板体积为(11.25±1.40)fL、血小板分布宽度为(13.27±2.07)fL、大型血小板比率为(37.68±4.96)fL,明显低于对照组的(2.04±0.58)mpa·s、(13.19±2.46)mpa·s、(6.73±0.71)mpa·s、(13.64±1.24)fL、(15.97±2.15)fL、(40.15±5.77)fL,差异均有统计学意义(P<0.05)。观察组治疗总有效率为94.50%,对照组治疗总有效率为80.00%,差异有统计学意义(P<0.05)。结论应用星蒌承气汤治疗中风痰热腑实证患者具有较好的临床效果,且能够改善血流动力学指标和血小板参数。

Objective To investigate the clinical effect of xingkirilou chengqi decoction in the treatment of stroke.Methods From February 2018 to March 2019,110 cases of stroke patients with phlegm heat and fufu were randomly divided into two groups with 55 cases in each group.The study group was treated with xinglou chengqi decoction,and the control group only received conventional treatment.The main TCM syndromes,hemodynamics,platelet parameters and clinical efficacy of the two groups were compared after treatment.Results After treatment,hemiplegia(4.37±0.63)points,partial body numbness(1.14±0.41)points,speech and motion asthenia(1.25±0.57)points,tongue asthenia(0.95±0.13)points,phlegm(0.68±0.18)points,headache(0.81±0.22)points,abdominal fullness(0.94±0.26)points,constipation(1.25±0.52)points,total score(11.42±1.27)points,significantly lower than the control group(5.66±0.75)points,(1.97±0.35)points,(2.03±0.41)points,(1.42±0.26)points,(1.44±0.39)points,(1.90±0.33)points,(2.17±0.57)points,(15.04±2.04)points,all of which had statistical significance(P<0.05).After treatment,plasma viscosity was(1.42±0.37)mpa·s,blood viscosity was(10.27±2.63)mpa·s,blood viscosity was(4.38±0.94)mpa·s,mean platelet volume was(11.25±1.40)fL,platelet distribution width was(13.27±2.07)fL,and large platelet ratio was(37.68±4.96)fL.The results were significantly lower than those of the control group(2.04±0.58)mpa·s,(13.19±2.46)mpa·s,(6.73±0.71)mpa·s,(13.64±1.24)fL,(15.97±2.15)fL,(40.15±5.77)fL,all of which were statistically significant(P<0.05).The total effective rate of the observation group was 94.50%,and that of the control group was 80.00%.The total effective rate of the two groups was statistically significant(P<0.05).Conclusion Xingtrichosanthes chengqi decoction has good clinical effect on patients with phlegm and heat fufu after stroke,and can improve hemodynamics and platelet parameters.