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肥胖的中枢发病机制及不同减重方式的中枢作用 被引量:3

The regulating mechanism of central nervous system on obesity and influence of weight loss on brain
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摘要 肥胖症的主要治疗难点在于减重后的体重维持及防止反弹。近年来,越来越多的研究发现肥胖症的发生发展与大脑的功能异常密不可分,而大脑在减重后的体重维持及反弹中也起着关键作用。本文综述了肥胖症发生过程中体重调控的中枢机制,并比较了常用的减重方法对中枢的影响和由此导致的减重效果的差异。期望减重应从病因出发,强调个体化治疗。基础与临床研究不可忽视中枢的调控。
作者 林紫薇 曲伸 Lin Ziwei;Qu Shen(Endocrinology and Metabolism Center,Tenth Peopled Hospital of Tongji University,National Metabolic Management Center(Shanghai Tenth People's Hospital),Shanghai 200072,China;Division of Metabolic Surgery for Obesity and Diabetes,Shanghai Tenth Peopled Hospital,Shanghai 200072,China)
出处 《中华内科杂志》 CAS CSCD 北大核心 2021年第2期160-165,共6页 Chinese Journal of Internal Medicine
基金 国家重点研发计划(2018YFC1314100) 国家自然科学基金面上项目(81970677) 国家自然科学基金青年科学基金(81500687) 上海市医药卫生发展基金会糖尿病临床研究项目(1期07研究) 同济大学中央高校基本科研业务费专项资金(22120190210)。
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