健脾疏肝止泻方治疗腹泻型肠易激综合征的临床疗效分析

Clinical analysis of Jianpi Shugan Zhixie decoction in the treatment of diarrhea-predominant irritable bowel syndrome

目的:探讨腹泻型肠易激综合征(Diarrhea-type Irritable Bowel Syndrome,IBS-D)疾病的患者使用健脾疏肝止泻方进行治疗的临床效果。方法:随机选择2019年6月-2020年6月于新兴县人民医院进行治疗的IBS-D患者50例,采用抽签的方式将所有患者分为对照组(25例)和治疗组(25例),其中对照组患者采用曲美布汀进行治疗,治疗组患者采用健脾疏肝止泻方进行治疗,比较两组患者的临床治疗效果。结果:治疗后治疗组的临床症状积分(2.66±2.03)分明显低于对照组(6.83±2.27)分(P<0.05);治疗30 d后,治疗组的总有效率96.00%(24/25)高于对照组76.00%(19/25),两组间差异具有统计学意义(P<0.05);停药60 d后,治疗组的总有效率92.00%(23/25)高于对照组60.00%(15/25),两组间差异有统计学意义(P<0.05)。结论:相较于西医疗法,针对IBS-D疾病的患者使用健脾疏肝止泻方进行治疗的临床效果更佳,应当推广应用。

Objective:To investigate the clinical effect of Jianpi Shugan Zhixie decoction(健脾疏肝止泻方)in the treatment of patients with IBS-D disease.Methods:Fifty patients with IBS-D who were treated in People's Hospital of Xinxing County from June 2019 to June 2020 were randomly selected.All patients were divided into the control group(25 cases)and the treatment group(25 cases)by lottery.The control group was treated with Trimebutine,and the patients in the treatment group were treated with Jianpi Shugan Zhixie decoction.The clinical effects of the two groups were compared.Results:After treatment,the clinical symptom scores of the treatment group(2.66±2.03)scores were significantly lower than those of the control group(6.83±2.27)scores(P<0.05).After 30 days of treatment,the total effective rate of the treatment group 96.00%(24/25)was higher than that of the control group 76.00%(19/25),the difference between the two groups was significant(P<0.05);after 60 days of withdrawal,the total effective rate of the treatment group 92.00%(23/25)was higher than that of the control group 60.00%(15/25),and the difference between the two groups was significant(P<0.05).Conclusion:Compared with the western medical method,the clinical effect of Jianpi Shugan Zhixie decoction is better in the treatment of patients with IBS-D disease,and it should be promoted and applied.