6例乳头状肾细胞癌患者的临床病理特征及预后研究

Clinicopathological features and prognosis of 6 patients with papillary renal cell carcinoma

目的:确定乳头状肾细胞癌的临床病理特征,提高乳头状肾细胞癌的诊治水平以改善患者预后。方法:选取鄄城县人民医院2016年6月-2019年6月诊治的乳头状肾细胞癌I型患者6例,患者行根治性肾切除术,并对患者进行临床病理特征分析与术后随访。结果:6例患者中,乳头状肾细胞癌分期结果为T_(1)期3例,T_(2)期2例,T_(3)期1例,病理分级结果为G_(1)4例,G_(2)2例。临床病理学检查中,发现乳头状肾细胞癌肿瘤大小为3~5 cm,有明显纤维性假包膜,乳头表面被覆单层立方细胞,轴心内富有含类脂的泡沫样巨噬细胞。6例患者随访资料中,随访时长为6个月~3年,其中1例患者肿瘤局部复发,其余5例患者无瘤生存。结论:乳头状肾细胞癌在临床上还是以根治性肾切除术为主要治疗方法,患者治疗后预后相对较好。

Objective:To determine the clinicopathological characteristics of papillary renal cell carcinoma,to improve the diagnosis and treatment level of papillary renal cell carcinoma and improve the prognosis of patients.Methods:Six patients with type I papillary cell carcinoma diagnosed and treated in Juancheng county people's hospital from June 2016 to June 2019 were selected and underwent radical nephrectomy.Results:Among the 6 patients,papillary renal cell carcinoma staging results showed there were 3 cases of T_(1) stage,2 cases of T_(2) stage,1 case of T_(3) stage 1;there were 4 cases of G_(1) and 2 cases of G_(2).In the clinicopathological examination,papillary renal cell carcinoma was found to have a tumor size of about 3-5 cm,with obvious fibrous pseudocapsule,the papillary surface was covered with monolayer cubic cells,and there were lipid-rich foam macrophages in the axis.In the follow-up data of 6 patients,the follow-up time was from 6 months to 3 years.Among them,1 patient had local tumor recurrence and the other 5 patients survived without tumor.Conclusion:Radical nephrectomy is the main treatment for papillary renal cell carcinoma,and the prognosis is relatively good.