从瘀毒郁互结探讨冠心病伴焦虑、抑郁的病机特点

Discussion on Coronary Heart Disease with Anxiety and Depression from the Pathogenesis of Binding of Stasis,Toxins,and Constraints

瘀毒致病理论是阐释冠心病发生发展的重要学说,情志致病(郁)在冠心病及冠心病伴焦虑、抑郁患者发病中具有重要作用。瘀、毒、郁常联合致病,使病情加重,迁延难愈。通过阐释瘀、毒、郁的内涵及在冠心病伴焦虑、抑郁中的发病机制,分析瘀毒、瘀郁、毒郁的相互关系和互结病机,总结瘀、毒、郁互结及三者相互影响促进是冠心病伴焦虑、抑郁的核心病机,活血、解毒、开郁同治,并根据瘀、毒、郁的不同程度随证加减,可作为冠心病伴焦虑、抑郁的治疗方法。

The concept of"stasis and toxins causing diseases"is a major theory to explain the incidence and progression of coronary heart disease(CHD).Moreover,improper emotions and minds(constraints)can also cause CHD,especially those with anxiety and depression.Pathogenic stasis,toxins and constraints often combine together,making the condition worse and refractory to the treatment.This paper explained the connotation of stasis,toxins and constraints,and their roles in the pathogenesis of CHD with anxiety and depression.The relationship between stasis-toxins,stasis-constraints,toxins-constraints were analyzed,and the pathogenesis of the binding of them were discussed.It was found that the binding and mutual influence of stasis,toxins and constraints was the core pathogenesis of CHD with anxiety and depression.Therefore,blood-invigorating,toxins-resolving,and constraints-discharging methods should be used simultaneously,and adjusted based on the different degree of stasis,toxins and constraints,in the treatment of CHD with anxiety and depression.